Evidence map›Paper›PMID 40210789›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Latent profile analysis and related factors for meaning in life among young and middle-aged cancer patients.

Shuman Wang, Wenjie Xu, Aoxing Sun, Zeling Zhang, Yu Zhang, Yu Zhu, Hongwei Wan

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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Cancer patients' perceptions of the meaning in life: a qualitative meta-synthesis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  2. Article
  3. Judicious use of latent profile analysis in supportive care: the distinction between mono- and multi-construct applications.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shuman WangDepartment of Nursing, Shanghai Proton and Heavy Ion Center, Fudan University Cancer Hospital, Proton Heavy Ion Hospital, Shanghai, China.
Wenjie XuDepartment of Nursing, Shanghai Proton and Heavy Ion Center, Fudan University Cancer Hospital, Proton Heavy Ion Hospital, Shanghai, China.
Aoxing SunDepartment of Nursing, Shanghai Proton and Heavy Ion Center, Fudan University Cancer Hospital, Proton Heavy Ion Hospital, Shanghai, China.
Zeling ZhangDepartment of Nursing, Shanghai Proton and Heavy Ion Center, Fudan University Cancer Hospital, Proton Heavy Ion Hospital, Shanghai, China.
Yu ZhangDepartment of Nursing, Shanghai Proton and Heavy Ion Center, Fudan University Cancer Hospital, Proton Heavy Ion Hospital, Shanghai, China.
Yu ZhuDepartment of Nursing, Shanghai Proton and Heavy Ion Center, Fudan University Cancer Hospital, Proton Heavy Ion Hospital, Shanghai, China.
Hongwei WanDepartment of Nursing, Shanghai Proton and Heavy Ion Center, Fudan University Cancer Hospital, Proton Heavy Ion Hospital, Shanghai, China. hong_whw@aliyun.com.

Funding

CSC scholarship program 202306100227Shanghai Pudong New District Science and Technology and Economic PKJ2024-Y56Shanghai Shenkang Hospital Development Center 2023SKMR-36Shanghai Shenkang Hospital Development Center SHDC12022620
6 · The paper itself

Abstract

purposeThis study identified different subgroups of meaning in life among young and middle-aged cancer patients, examined the sociodemographic and disease-related factors associated with these subgroups, and explored the correlation between these subgroups and psychological distress and post-traumatic growth.

methodsA total of 500 young and middle-aged cancer patients aged 18 to 59 completed the sociodemographic and disease-related questionnaire, the Purpose in Life Test, the Chinese version of the Posttraumatic Growth Inventory, and the Distress Thermometer. Latent profile analysis and multivariate logistic regression analysis were used to explore the subgroups of meaning in life and their associated socio-demographic and disease-related factors. Linear regression was used to investigate the correlation between these subgroups and psychological distress and post-traumatic growth.

resultsThe meaning in life among young and middle-aged cancer patients can be categorized into three profiles: low, moderate, and high meaning groups. The results of the multivariate logistic regression showed that age, gender, educational level, financial stress, disease duration, presence of commercial insurance, and family history were significant factors associated with the subgroups of meaning in life. Linear regression analysis indicated that meaning in life was negatively correlated with psychological distress and positively correlated with post-traumatic growth.

conclusionsThe meaning in life among young and middle-aged cancer patients was heterogeneous. Healthcare providers should develop and offer targeted intervention strategies based on the characteristics of different subgroups to enhance their meaning in life, thereby maintaining good psychological health.

Indexed as

NeoplasmsPosttraumatic Growth, PsychologicalQuality of LifeAdolescentAdultAge FactorsChinaFemaleHumansLinear ModelsLogistic ModelsMaleMiddle AgedPsychological DistressSex FactorsSocioeconomic FactorsCancerLatent profile analysisMeaning in lifeOncologyYoung and middle-aged

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.