Observational studyEuropean journal of clinical pharmacology2025
Drug-related falls: proportion and impact of hospitalizations in geriatric departments on the prescription of fall-risk increasing drugs (FRIDs).
Observational study in European journal of clinical pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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Who cites it
2 citing papers in PubMed.
- Secondary Prevention Bundle for Drug-Related Problems in an Integrated Healthcare Setting: A Pragmatic Observational Implementation-Effectiveness Study.Pharmacy (Basel, Switzerland) · 2026Article
- Falls in older patients treated for cancer in French outpatient departments: screening and prevention-a prospective observational study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Observational
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe incidence of drug-related admissions in France was 8.5% in 2018, with falls being the 5 th cause of DRA. The screening of adverse drug reactions (ADRs) in old adults can be challenging. Our objective was to determine the proportion of old patients hospitalized for drug-related falls in a geriatrics department, assess their preventability and the impact of hospitalizations on the prescription of fall-risk increasing drugs (FRIDs).
methodsA retrospective observational study, including patients aged over 75 years who were admitted to an acute geriatrics medicine department from May 10, 2022, to February 2, 2023, was conducted. We used a previously published method to detect DRA and assess their preventability.
resultsOf the 512 patients admitted to the department during the study period, 104 patients (20%) were hospitalized due to falls, of whom 71 (14%) were considered to be drug-related. Falls associated with drugs were categorized as more severe (p = 0.01). In 41% of drug-related falls, ADRs were considered to be definitively avoidable. The most commonly implicated FRIDs classes were beta-blockers (53%, n = 38); diuretics (47%, n = 34); antidepressants (41%, n = 29); benzodiazepines (6%, n = 20); and underuse of vitamin D in patients with a documented deficiency (65%, n = 46). In patients hospitalized for drug-related falls, the FRIDs decreased between admission (n = 314) and discharge (n = 198, p < 0.01).
conclusionThe proportion of hospitalizations for drug-related falls is notably high in geriatric department, and a substantial proportion can be prevented. These findings emphasize the importance of targeting high-risk patients for falls and implementing preventive measures, such as reassessing their medication as recommended in the latest international guidelines for falls prevention.
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