Evidence map›Paper›PMID 40210113›Full record

ArticleThe Journal of investigative dermatology2025

Ethacrynic Acid Mitigates Skin Fibrosis through Downregulation of S100 Family Damage-Associated Molecular Pattern Expression in the Epidermis.

David M Dolivo, Adrian E Rodrigues, Thomas A Mustoe, Robert D Galiano, Seok Jong Hong

Abstract read
In one paragraph

Article in The Journal of investigative dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David M DolivoDepartment of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Adrian E RodriguesDepartment of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Thomas A MustoeDepartment of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Robert D GalianoDepartment of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. Electronic address: rgaliano@nm.org.
Seok Jong HongDepartment of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. Electronic address: seok-hong@northwestern.edu.

Funding

Identification of therapeutic small molecules for treatment of skin fibrosis by modulating epidermal pro-inflammatory signalingR21AR081475 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HONG, SEOK JONG · 2022 to 2023
$387k
NIAMS NIH HHS R21 AR081475
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Connectivity map (CMap)Drug repurposingEpidermal–dermal interactionEthacrynic acidFibrosis

Identifiers

PMID40210113
PMCPMC12354136

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.