Evidence map›Paper›PMID 40209513›Full record

SynthesisClinical neurology and neurosurgery2025

Efficacy and safety of surpass evolve flow diverters: A systematic review and meta-analysis.

Seyed Behnam Jazayeri, Abdullah Reda, Jonathan Cortese, Aryan Gajjar, Sherief Ghozy, Ramanathan Kadirvel, David F Kallmes

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Clinical neurology and neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Seyed Behnam JazayeriTehran University of Medical Sciences, Tehran, Iran; Department of Radiology, Mayo Clinic, Rochester, MN, USA. Electronic address: Drbehnamjazayeri@gmail.com.
Abdullah RedaDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Jonathan CorteseDepartment of Radiology, Mayo Clinic, Rochester, MN, USA; Department of Interventional Neuroradiology (NEURI Vascular Center), Bicetre University-Hospital, Le Kremlin-Bicetre, France.
Aryan GajjarDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Sherief GhozyDepartment of Radiology, Mayo Clinic, Rochester, MN, USA; Department of Neurological Surgery, Mayo Clinic, Rochester, MN, USA.
Ramanathan KadirvelDepartment of Radiology, Mayo Clinic, Rochester, MN, USA; Department of Neurological Surgery, Mayo Clinic, Rochester, MN, USA.
David F KallmesDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.

Funding

Computational and Biological Approach to Flow DiversionR01NS076491 · NINDS · MAYO CLINIC ROCHESTER · PI Juan R Cebral, DAVID F KALLMES · 2011 to 2026
$7.4M
NINDS NIH HHS R01 NS076491NINDS NIH HHS R01NS076491
6 · The paper itself

Abstract

objectiveTo provide cumulative evidence on the safety and efficacy of the Surpass Evolve Flow Diverters (SE-FDs) in treating intracranial aneurysms.

methodsPubMed, Scopus, Embase, and Web of Science were searched until May, 2024. The primary efficacy endpoint was complete occlusion rate, and the safety endpoints included rate of different complications and mortality. Data is pooled and reported with 95 % confidence intervals (CIs) using random-effect models. A meta-regression analysis was performed to assess the potential effects of confounding factors on study endpoints.

resultsEleven studies with 690 patients and 757 aneurysms were included. There was moderate risk of bias in all studies. With a median follow-up of 243 days, the complete occlusion rate was 67.1 % (95 %CI: 57.3-75.5 %, I

conclusionsSE-FD is effective for treating intracranial aneurysms, with moderate efficacy compared to other devices and an acceptable rate of complications. Larger aneurysm size predicts lower occlusion rates. The lack of controlled trials warrants further research to explore the efficacy and safety of SE-FDs in clinical practice.

Indexed as

Endovascular ProceduresIntracranial AneurysmStentsHumansTreatment OutcomeFlow divertersFunctional independenceIntracranial aneurysmsMortalitySafetySurpass evolve

Identifiers

PMID40209513
PMCPMC13637687

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.