Evidence map›Paper›PMID 40209087›Full record

Trial reportAmerican journal of respiratory and critical care medicine2025

Comparison of Prophylactic and Therapeutic Doses of Anticoagulation for Acute Chest Syndrome in Sickle Cell Disease: The TASC Double-Blind Controlled Randomized Clinical Trial.

Armand Mekontso Dessap, Anoosha Habibi, Jean-Benoît Arlet, Muriel Fartoukh, Laurent Guerin, Constance Guillaud, Damien Roux, Johanna Oziel, Stéphanie Ngo, Benjamin Carpentier and 15 more

Abstract readRandomized Controlled TrialComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Trial report in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Sickle cell disease: managing thromboembolism.Hematology. American Society of Hematology. Education Program · 2025
    Review
  3. Let's Not Keep Acute Chest Syndrome Under an Umbrella.American journal of respiratory and critical care medicine · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors.

Armand Mekontso DessapService de Médecine Intensive Réanimation.ORCID 0000-0001-5961-5577
Anoosha HabibiUnité des Maladies Génétiques du Globule Rouge, Centre de référence Syndromes Drépanocytaires Majeurs.
Jean-Benoît ArletDepartment of Internal Medicine, French National Reference Center for Sickle Cell Disease, Thalassemia and Other Red Blood Cell and Erythropoiesis Disorders and.
Muriel FartoukhGroupe de Recherche Clinique CARMAS, Institut Mondor de Recherche Biomédicale, Université Paris Est Créteil, Créteil, France.
Laurent GuerinService de Médecine Intensive Réanimation, Hôpital Bicêtre, AP-HP, Le Kremlin-Bicêtre, France.
Constance GuillaudDépartement d'Aval des Urgences.
Damien RouxService de Médecine Intensive Réanimation, DMU ESPRIT, Université Paris Cité and.ORCID 0000-0002-6103-6416
Johanna OzielService de Réanimation Médico-Chirurgicale, Hôpital Avicenne, AP-HP, Université Sorbonne Paris Nord, Bobigny, France.
Stéphanie NgoService de Médecine Interne and.
Benjamin CarpentierService d'Hématologie Clinique, Hôpital Saint Vincent de Paul, Groupe Hospitalier de l'Institut Catholique de Lille, Lille, France.
Marilucy Lopez-SubletService de Médecine Interne, Centre d'Excellence Européen en Hypertension Artérielle, Hôpital Avicenne, AP-HP, Avicenne, France.
Louis AffoService de Médecine Interne, AP-HP, Hôpital Louis Mourier, AP-HP, Colombes, France.
Giovanna MelicaService d'Immunologie Clinique et Maladies Infectieuses.
Maryse Etienne-JulanUnité Transversale de la Drépanocytose, Centre de Référence Syndromes Drépanocytaires Majeurs, CHU de la Guadeloupe, Pointe-à-Pitre, France.
Isabelle DelacroixService de Médecine Interne and.
François LionnetService de Médecine Interne, Hôpital Tenon, AP-HP, Sorbonne Université, Hôpital Tenon, Paris, France.
Gylna LokoCentre de la Drépanocytose, CHU de Martinique, Le Lamentin, France.
Daniel Da SilvaService de Médecine Intensive Réanimation, Hôpital Delafontaine, Saint-Denis, France.
Marc MichelService de Médecine Interne, and.
Keyvan RazaziService de Médecine Intensive Réanimation.ORCID 0000-0001-7979-2650
Anaïs Charles-NelsonUnité de Recherche Clinique, Hôpital Européen Georges Pompidou, AP-HP, Paris-Cité University, Paris, France.
Pablo BartolucciUnité des Maladies Génétiques du Globule Rouge, Centre de référence Syndromes Drépanocytaires Majeurs.
Ségolène GendreauService de Médecine Intensive Réanimation.ORCID 0000-0002-8223-4411
Sandrine KatsahianUnité de Recherche Clinique, Hôpital Européen Georges Pompidou, AP-HP, Paris-Cité University, Paris, France.
Bernard MaitreUnité de Pneumologie, Hôpitaux Universitaires Henri-Mondor, AP-HP, Créteil, France.

Funding

Assistance Publique-Hôpitaux de ParisLEO Pharma
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acute Chest SyndromeAnemia, Sickle CellAnticoagulantsAdultDouble-Blind MethodFemaleFranceHemorrhageHumansMaleMiddle AgedTreatment OutcomeYoung AdultAnticoagulantsacute chet syndromeanticoagulationsickle cell diseasetinzaparin

Identifiers

PMID40209087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.