Evidence map›Paper›PMID 40208939›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Arf1 and ARFGEF2/Sec71 control neuroblast polarity by anchoring nonmuscle myosin II.

Mahekta R Gujar, Ye Sing Tan, Yang Gao, Hongyan Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mahekta R GujarNeuroscience & Behavioral Disorders Programme, Duke-National University of Singapore Medical School, 169857, Singapore.ORCID 0000-0001-8702-4352
Ye Sing TanNeuroscience & Behavioral Disorders Programme, Duke-National University of Singapore Medical School, 169857, Singapore.ORCID 0000-0002-4840-1853
Yang GaoNeuroscience & Behavioral Disorders Programme, Duke-National University of Singapore Medical School, 169857, Singapore.ORCID 0000-0001-6357-7470
Hongyan WangNeuroscience & Behavioral Disorders Programme, Duke-National University of Singapore Medical School, 169857, Singapore.ORCID 0000-0003-4623-1878

Funding

Khoo Bridge Funding Award KBrFA/2023/0073
6 · The paper itself

Abstract

Neural stem cells (NSCs) can self-renew and undergo differentiation via asymmetric division. Dysregulation in the balance between self-renewal and differentiation can lead to tumor formation or neurodevelopmental disorders. However, the regulation of phosphatidylinositol transfer protein (PITP)-dependent PI(4)P pools and myosin localization during asymmetric division in dividing cells is not well established. Here, we show that the Golgi proteins Arf1 and ARFGEF2/Sec71 control asymmetric division of

Indexed as

ADP-Ribosylation Factor 1Cell PolarityDrosophila ProteinsGuanine Nucleotide Exchange FactorsMyosin Type IINeural Stem CellsAnimalsDrosophilaDrosophila melanogasterGolgi ApparatusPhosphatidylinositol PhosphatesADP-Ribosylation Factor 1Drosophila ProteinsGuanine Nucleotide Exchange FactorsMyosin Type IIphosphatidylinositol 4-phosphatePhosphatidylinositol Phosphatesasymmetric cell divisionDrosophilaGolginonmuscle myosin IIphosphatidylinositol lipids

Identifiers

PMID40208939
PMCPMC12012615

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.