ArticlePLoS neglected tropical diseases2025
Point-of-care ultrasound reveals extensive pathology in Gabonese preschool-age children with urogenital schistosomiasis.
Article in PLoS neglected tropical diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Ultrasound evaluation of urinary tract morbidity in adults living in a Schistosoma haematobium endemic region in Mozambique.BMC infectious diseases · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
backgroundHistorically, urinary tract pathology caused by S. haematobium infection was thought to affect predominantly school-age children (SAC) and adults. Increasing availability of ultrasound data from endemic areas demonstrates that even younger children develop potentially irreversible pathology. METHODOLOGY/PRINCIPAL
findingsPoint-of-care ultrasound for urinary schistosomiasis and urine microscopy were performed across age groups in 105 patients with symptomatic urogenital schistosomiasis in Lambaréné, Gabon. Of 96 ultrasound scans with sufficient image quality, bladder wall thickening > 5mm was found in 9/20 (45%) preschool-age children (PSAC), 29/51 (57%) SAC and 7/25 (28%) adults. Upper urinary tract pathology was found in 19/90 (21%) patients across age groups, up from three years of age. Urine egg counts were highest in PSAC, with high-intensity infection (≥ 50 eggs/10 ml urine) in 19/24 (79%) and hyper-infection (≥ 500 eggs/10 ml urine) in 10/24 (42%). Bladder wall thickening > 5mm and upper urinary tract pathology correlated significantly with high-intensity infection with crude odds ratios of 8.6 (95% CI 3.1-23.8; p<0.001) and 6.6 (95% CI 1.4-30.7; p=0.02), respectively. Three months after praziquantel treatment, parasitology showed a cure rate of 51% and egg reduction rate of 95%, while bladder wall thickening and upper urinary tract pathology persisted in 12/41 (29%) and 7/12 (58%) patients. CONCLUSIONS/SIGNIFICANCE: A high proportion of PSAC in areas endemic for urogenital schistosomiasis already have detectable urinary tract pathology. Our findings highlight the urgent need to include this age group in mass drug administration programs, as recommended now by WHO. Further, particular attention should be paid to individual patient care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.