Identification, In Silico Screening, Inhibition Mechanisms to Keap1 and Angiotensin-I-Converting Enzyme, and Ferrous-Transport Capacity of a Multifunctional Octapeptide from Camellia oleifera Globulin.

Yan Li, Yong Yang, Chen Feng, Jie Liu, Jing Wang, Luchen Wang

Abstract read

In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

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Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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5 · Who and what money

Authors and funding

6 authors.

Yan Li *Food Science College of Shanxi Normal University, Taiyuan, 030031, China. liy.12348@163.com.

Yong Yang *Shanxi Province Cancer Hospital, Taiyuan, 030013, China.

Chen FengFood Science College of Shanxi Normal University, Taiyuan, 030031, China.

Jie LiuFood Science College of Shanxi Normal University, Taiyuan, 030031, China.

Jing WangFood Science College of Shanxi Normal University, Taiyuan, 030031, China.

Luchen WangFood Science College of Shanxi Normal University, Taiyuan, 030031, China.

Funding

Natural Science Foundation for Young Scientists of Shanxi Province 202203021221139

6 · The paper itself

Abstract

Camellia oleifera expeller is an abundant protein resource, but its usage in food is limited. In this study, potential antioxidant and hypotensive peptides with ferrous-chelating activity were isolated, identified, and virtually screened from camellia expeller globulin hydrolysates. The action mechanisms against Keap1 and angiotensin-I-converting enzyme (ACE), gastrointestinal stability, and ferrous-transmembrane absorption were studied. After in silico screening, a safe multifunctional octapeptide: Ser-Gly-Tyr-Gly-Tyr-Gly-Tyr-Gly (SGYGYGYG) was obtained. SGYGYGYG showed high ACE-restraining ability of IC

Indexed as

Angiotensin-Converting Enzyme InhibitorsCamelliaGlobulinsKelch-Like ECH-Associated Protein 1OligopeptidesPeptidyl-Dipeptidase AAntioxidantsComputer SimulationFerrous CompoundsHumansIron Chelating AgentsNF-E2-Related Factor 2Plant ProteinsAngiotensin-Converting Enzyme InhibitorsAntioxidantsFerrous CompoundsGlobulinsIron Chelating AgentsKEAP1 protein, humanKelch-Like ECH-Associated Protein 1NF-E2-Related Factor 2OligopeptidesPeptidyl-Dipeptidase APlant ProteinsAngiotensin-I-Converting enzymeCamellia oleifera globulin peptidesFerrous absorptivityInhibition mechanismsKeap1Stability

Identifiers

PMID40208474

DOI10.1007/s11130-025-01352-5

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.