Evidence map›Paper›PMID 40208319›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2025

Potent cytotoxicity and induction of ROS-mediated genomic instability, mitochondrial dysfunction, and apoptosis by Y

Hanan R H Mohamed, Rawan Essam, Basma A Mohamed, George M Hakeem, Shahd H Elnawasani, Maria Nagy, Gehan Safwat, Ayman Diab

Abstract read
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Blue light activated nitrogen doped poly floral carbon quantum dots: multifunctional agent for anti-microbial and anti-cancer photodynamic therapy.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hanan R H MohamedDepartment of Zoology, Faculty of Science, Cairo University, Giza, Egypt. hananeeyra@cu.edu.eg.
Rawan EssamFaculty of Biotechnology, October University for Modern Sciences and Arts (MSA), 6Th of October City, Egypt.
Basma A MohamedFaculty of Biotechnology, October University for Modern Sciences and Arts (MSA), 6Th of October City, Egypt.
George M HakeemFaculty of Biotechnology, October University for Modern Sciences and Arts (MSA), 6Th of October City, Egypt.
Shahd H ElnawasaniFaculty of Biotechnology, October University for Modern Sciences and Arts (MSA), 6Th of October City, Egypt.
Maria NagyFaculty of Biotechnology, October University for Modern Sciences and Arts (MSA), 6Th of October City, Egypt.
Gehan SafwatFaculty of Biotechnology, October University for Modern Sciences and Arts (MSA), 6Th of October City, Egypt.
Ayman DiabFaculty of Biotechnology, October University for Modern Sciences and Arts (MSA), 6Th of October City, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic cancer, one of the most prevalent and lethal cancers globally, remains a significant health challenge, with limited treatment options underscoring the urgent need for novel, more effective therapies. Yttrium oxide nanoparticles (Y

Indexed as

Antineoplastic AgentsLiver NeoplasmsMitochondriaReactive Oxygen SpeciesYttriumApoptosisCell SurvivalDNA DamageGenomic InstabilityHep G2 CellsHumansMembrane Potential, MitochondrialAntineoplastic AgentsReactive Oxygen SpeciesyttriaYttriumGenomic InstabilityHepatic cancerMitochondrial dysfunction and apoptosis inductionYttrium oxide nanoparticles

Identifiers

PMID40208319
PMCPMC12449341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.