Evidence map›Paper›PMID 40208306›Full record

ArticleAnimal biotechnology2025

Identifying sex-based disparities in porcine mitochondrial function.

Hao Liu, Wenshu Shi, Xing Zhang, Xinmiao He, Xingbo Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animal biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hao LiuDepartment of Gastroenterology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Wenshu ShiState Key Laboratory of Animal Biotech Breeding, China Agricultural University, Beijing, China.
Xing ZhangState Key Laboratory of Animal Biotech Breeding, China Agricultural University, Beijing, China.
Xinmiao HeInstitute of Animal Husbandry, Heilongjiang Academy of Agricultural Sciences, Harbin, China.
Xingbo ZhaoState Key Laboratory of Animal Biotech Breeding, China Agricultural University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In pigs, the effect of sex on production and reproductive traits has been largely reported, however, whether sex exerts its influence through regulating mitochondrial function is still unclear. In this study, we constructed 15 male cells and 15 female fibroblasts derived from 35-day and 50-day fetuses, newborn piglets and 1-year-old pigs to identify the sex effect on mitochondrial functions. Results indicated significant differences on cellular and molecular characteristics between male and female cells, including energy metabolic trait, mitochondrial DNA (mtDNA) replication and transcription, and mRNA expressions of mitochondrial biogenesis genes and mitoprotease genes. Referring to sex, males exhibited significantly higher oxygen consumption rate productions, levels of reactive oxygen species (ROS) and mtDNA copy numbers than those with females in muscle and ear fibroblasts. And the expressions of mtDNA, mitochondrial biogenesis genes (

Indexed as

MitochondriaSex CharacteristicsAnimalsCells, CulturedDNA, MitochondrialEnergy MetabolismFemaleFibroblastsMaleReactive Oxygen SpeciesSex FactorsSwineDNA, MitochondrialReactive Oxygen Speciesmitochondrionoxygen consumption rateporcinereactive oxygen speciesSex

Identifiers

PMID40208306
PMCPMC12674342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.