ArticleJournal of public health (Oxford, England)2025
Anxiety and hypertension in young and middle-aged adults: a longitudinal cohort study.
Article in Journal of public health (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Identification of Mental Health Disorder Symptoms, Predisposing Factors and their Impact on Quality of Life in Young Hypertensive Patients: A Multicenter Longitudinal Study.Clinical practice and epidemiology in mental health : CP & EMH · 2026Article
- The Overlooked Driver of Hypertension: Mental Stress at the Crossroad of Cardiology and Psychiatry.Current atherosclerosis reports · 2025Review
- Stress, Anxiety, and Self-Efficacy in Hypertension: Evidence from a Romanian Case-Control Study.Diseases (Basel, Switzerland) · 2025Article
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2 authors.
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Abstract
backgroundThere is a significant prevalence of hypertension among younger and middle-aged adults. Anxiety is a potential psychosocial risk factor, but there is mixed evidence regarding this association in younger adults.
methodsThis study analyzed data from the National Longitudinal Study of Adolescent to Adult Health, focusing on Waves 4 and 5, to explore the relationship between anxiety and incident hypertension in 9283 participants. Incident hypertension was classified first with objective blood pressure measures and antihypertensive medication use and, secondly, including self-reported diagnosis. Anxiety was identified in Waves 4 and 5, including age at diagnosis. Analyses used multivariable logistic regression and Cox proportional hazards models with anxiety treated as a time-dependent predictor.
resultsThe average age was ~29 at Wave 4 and ~37 at Wave 5. Results showed mixed evidence, with no significant association between prior anxiety and objectively measured hypertension. However, including self-reported hypertension, a prior diagnosis of anxiety was associated with incident hypertension (aOR = 0.76, 95% CI: 0.63-0.92). Time-to-event analyses further supported this inverse relationship.
conclusionThis study found some evidence suggesting an inverse relationship between anxiety and incident hypertension in young to middle-aged adults, warranting further longitudinal research into the complex relationship between mental and cardiovascular health.
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