ArticleCurrent medical imaging2025
Efficacy of Thrombin Solution Injection Combined with Rapid Biopsy-Side Down Position Technique in CT–guided Lung Biopsy: A Propensity Score Matching Analysis
Article in Current medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThe objective of this study is to investigate the effect of thrombin solution injection combined with the rapid biopsy-side down position technique on the incidence of pneumothorax in emphysema patients following computed tomography (CT)-guided lung biopsy based on propensity score matching. MATERIALS &
methodsA retrospective study was conducted on emphysema patients who underwent CT-guided percutaneous lung biopsy between May 2022 and July 2023. Patients were divided into two groups based on the use of the rapid biopsy-side-down position technique. Propensity score matching was then applied to explore correlations.
resultsA total of 212 patients were included in the study. Before propensity score matching, there were no significant differences between Groups A and B in terms of sex, lesion size, puncture path length, or patient positioning in multivariate logistic regression analysis. After matching with a 1:1 ratio, 41 patients were successfully paired. Logistic regression analysis revealed that the rapid biopsy-side down position technique was significantly correlated with a reduced incidence of pneumothorax (p = 0.027), serving as a protective factor.
conclusionThe combination of thrombin solution injection and the rapid biopsy-side down position technique significantly reduces the incidence of pneumothorax in emphysema patients following CT-guided lung biopsy.
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