Evidence map›Paper›PMID 40207594›Full record

ArticleEmergency medicine Australasia : EMA2025

Characteristics and predictors of severe outcomes of COVID-19 cases presenting to the emergency department of a major Australian referral hospital: A record linkage study.

Katrina Boldt, Nectarios Rose, Sandra Ware, Michael M Dinh, Kishor Kumar Paul, Yvonne Ho, David J Muscatello

Abstract read
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Article in Emergency medicine Australasia : EMA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Katrina BoldtSchool of Population Health, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0009-0007-3042-6837
Nectarios RoseSchool of Population Health, University of New South Wales, Sydney, New South Wales, Australia.
Sandra WareGreater Sydney Helicopter Emergency Medical Service, NSW Ambulance, Sydney, New South Wales, Australia.
Michael M DinhEmergency Department, RPA Green Light Institute, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
Kishor Kumar PaulSchool of Population Health, University of New South Wales, Sydney, New South Wales, Australia.
Yvonne HoNSW Biostatistics Training Program, NSW Ministry of Health, Sydney, New South Wales, Australia.
David J MuscatelloSchool of Population Health, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0002-2391-4396

Funding

National Health and Medical Research Council APP1194109
6 · The paper itself

Abstract

objectiveTo describe the characteristics, outcomes and predictors of a severe outcome of patients presenting with a SARS-CoV-2 infection to the ED of a major urban referral hospital in New South Wales, Australia, from January 2020 through February 2022.

methodsLinked healthcare and death registration records were used and included any person assigned a diagnosis potentially related to an acute respiratory infection in the ED and that had a linked positive COVID-19 detection. Logistic regression was used to determine predictors of a severe outcome (ICU admission or death) within 28 days.

resultsOf 2081 included COVID-19 patients, 238 (11.4%) had a severe outcome within 28 days of arrival at the ED. Among adults, the odds of a severe outcome increased with age, although the rate of increase in odds within age groups was statistically significant only in 30-64-year-olds (4% per year of age; confidence interval [CI] 2-6). Ambulance arrival (odds ratio [OR] 2.85; CI 1.76-4.78), higher triage urgency (category 1 or 2 compared with 4 or 5: OR 8.63; CI 4.41-18.12), and presentation during the pre-Delta (OR 6.18; CI 3.59-10.66) and Delta (OR 3.64; 95% CI 2.49-5.35) variant periods (compared with Omicron) were independently associated with increased risk of a severe outcome.

conclusionAge, ambulance arrival, higher triaged urgency, and presentation earlier in the pandemic were predictors of a severe COVID-19 outcome. Aged care measures and prioritising vaccination of older persons and aged care workers may have reduced severe outcomes in the elderly.

Indexed as

COVID-19Emergency Service, HospitalAdolescentAdultAgedAged, 80 and overAge FactorsChildFemaleHumansMaleMiddle AgedNew South WalesSARS-CoV-2Severity of Illness IndexTriageCOVID‐19emergency departmenthealthcare datahospitalisationlinked data

Identifiers

PMID40207594
PMCPMC11983665

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.