ArticleJournal of the American Heart Association2025
Association Between First-Phase Left Ventricular Ejection Fraction and Severity of Coronary Artery Stenosis and Changes With Interventional Treatment.
Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- First-phase ejection fraction and ventricular-arterial coupling across the lifespan: An in silico analysis.Physiological reports · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMyocardial ischemia can impair the speed and intensity of myocardial contractility, frequently undetectable by conventional echocardiography in early stages. The aim of this study was to assess whether first-phase left ventricular ejection fraction (LVEF-1), a sensitive myocardial contractility marker, correlates with ischemia severity and improves following interventional treatment. METHODS AND
resultsTwo hundred seven patients were categorized into mild, moderate, and severe groups based on angiographic coronary maximal stenosis. LVEF-1, Gensini scores, and clinical data were compared among these groups. Logistic regression was used to assess the association between LVEF-1 and coronary artery stenosis, and linear regression identified factors linked to postintervention LVEF-1 improvement. The median LVEF-1 in the 3 groups was 29.6% (28.2-31.7), 27.8% (27.0-28.6), and 25.2% (23.6-26.5) (
conclusionsLVEF-1 is negatively correlated with the severity of coronary artery stenosis, and it improves significantly after coronary artery intervention therapy, suggesting that LVEF-1 can serve as a novel indicator for assessing coronary artery stenosis severity and monitoring the efficacy of interventional treatment.
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