ArticleJournal of the American Heart Association2025
Association Between Cumulative Body Mass Index Exposure and the Risk of Incident Cardiac Conduction Block.
Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Sex-Specific Associations of Triglyceride-Glucose Index and a Body Shape Index with Cardiometabolic Multimorbidity Risk: A Prospective Cohort Study.Journal of clinical medicine · 2026Article
- Cumulative effects of excess weight, sleep quality, and depressive and anxiety symptoms in Chinese adolescents.BMC psychology · 2026Article
- Article
- Genomic Structural Equation Modeling Combined With Post-GWAS Analysis Identifies Two Risk Gene Loci and Functionally Sensitive Genes Associated With Cardiac Conduction Block.Genetics research · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationship between cumulative body mass index (cumBMI) exposure and cardiac conduction block (CCB) is not fully understood. This study aimed to explore the association between cumBMI and the risk of CCB. METHODS AND
resultsA total of 107 860 participants of the Kailuan Study were included. Participants were then categorized into 4 groups based on their quartile of cumBMI. The association of cumBMI with CCB was estimated using the Cox proportional hazards regression model. During a median follow-up of 8.36 years, 1894 CCBs, 586 atrioventricular blocks (AVBs), 1273 intraventricular blocks, 851 right bundle branch blocks, and 319 any left bundle branch blocks occurred. After adjusting for potential confounders, the hazard ratios for CCB, atrioventricular block, intraventricular block, right bundle branch block, and any left bundle branch block were 1.86 (95% CI, 1.60-2.18), 2.51 (95% CI, 1.90-3.32), 1.55 (95% CI, 1.28-1.87), 2.14 (95% CI, 1.69-2.71), and 1.18 (95% CI, 0.81-1.72) for individuals in the highest quartile of cumBMI compared with those in the second quartile, respectively. Additionally, the subgroup analyses showed significant interactions between age, sex, and cumBMI for developing CCB (
conclusionsOur findings suggest that higher cumulative BMI exposure significantly increased the risk of CCB, especially atrioventricular block. Monitoring cumulative BMI may help to identify high-risk CCB populations.
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