Evidence map›Paper›PMID 40207358›Full record

ArticleCirculation. Genomic and precision medicine2025

Clonal Hematopoiesis of Indeterminate Potential in Chronic Coronary Disease: A Report From the ISCHEMIA Trials Biorepository.

Matthew A Muller, Richard Liu, Farheen Shah, Jiyuan Hu, Claes Held, Iftikhar J Kullo, Bruce M McManus, Lars Wallentin, L Kristin Newby, Mandeep S Sidhu and 7 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation. Genomic and precision medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Matthew A MullerDepartment of Biomedical Engineering, New York University Tandon School of Engineering (M.M.).ORCID 0000-0002-5079-1889
Richard LiuDepartment of Population Health, Division of Biostatistics (R.L.).ORCID 0009-0002-2475-5814
Farheen ShahDepartment of Medicine (F.S., S.B., H.R.R., J.S.H., K.V.R., J.S.B., J.D.N.).ORCID 0009-0000-2194-6573
Jiyuan HuNYU Grossman School of Medicine (M.M., J.H.).ORCID 0000-0003-1332-5587
Claes HeldDepartment of Medical Sciences, Cardiology, Uppsala University, Sweden (C.H., L.W.).ORCID 0000-0001-9402-7404
Iftikhar J KulloDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (I.J.K.).ORCID 0000-0002-6524-3471
Bruce M McManusDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada (B.M.M.).
Lars WallentinDepartment of Medical Sciences, Cardiology, Uppsala University, Sweden (C.H., L.W.).ORCID 0000-0003-0378-6531
L Kristin NewbyDepartment of Medicine, Division of Cardiology, Duke Clinical Research Institute, Durham, NC (L.K.N.).ORCID 0000-0002-6394-8187
Mandeep S SidhuAlbany Medical College, NY (M.S.S.).
Sripal BangaloreDepartment of Medicine (F.S., S.B., H.R.R., J.S.H., K.V.R., J.S.B., J.D.N.).ORCID 0000-0001-9485-0652
Harmony R ReynoldsDepartment of Medicine (F.S., S.B., H.R.R., J.S.H., K.V.R., J.S.B., J.D.N.).ORCID 0000-0003-0284-0655
Judith S HochmanDepartment of Medicine (F.S., S.B., H.R.R., J.S.H., K.V.R., J.S.B., J.D.N.).ORCID 0000-0002-5889-5981
David J MaronDepartment of Medicine, Stanford University School of Medicine, CA (D.J.M.).ORCID 0000-0002-4867-8588
Kelly V RugglesDepartment of Medicine (F.S., S.B., H.R.R., J.S.H., K.V.R., J.S.B., J.D.N.).ORCID 0000-0002-0152-0863
Jeffrey S BergerDepartment of Medicine (F.S., S.B., H.R.R., J.S.H., K.V.R., J.S.B., J.D.N.).ORCID 0000-0001-8216-4647
Jonathan D NewmanDepartment of Medicine (F.S., S.B., H.R.R., J.S.H., K.V.R., J.S.B., J.D.N.).ORCID 0000-0001-6855-7305

Funding

The Ischemia Trial - CCCU01HL105907 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HOCHMAN, JUDITH S · 2011 to 2019
$100.1M
The ISCHEMIA Trial - SDCCU01HL105462 · NHLBI · DUKE UNIVERSITY · PI ALEXANDER, KAREN P, O'BRIEN, SEAN M · 2011 to 2019
$17.8M
THE ISCHEMIA TRIAL - IICCU01HL105561 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SHAW, LESLEE J · 2011 to 2018
$6.5M
Molecular predictors of cardiovascular events and resilience in chronic coronary artery diseaseR01HL165208 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JONATHAN D NEWMAN, Kelly Valentine Ruggles · 2023 to 2026
$3.0M
The ISCHEMIA Trial - EQOLU01HL105565 · NHLBI · DUKE UNIVERSITY · PI MARK, DANIEL B · 2011 to 2017
$2.4M
Molecular predictors of resistance and vulnerability to cardiovascular events in stable ischemic heart diseaseR56HL155528 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI NEWMAN, JONATHAN D, RUGGLES, KELLY VALENTINE · 2021 to 2021
$492k
NHLBI NIH HHS R01 HL165208NHLBI NIH HHS R56 HL155528NHLBI NIH HHS U01 HL105462NHLBI NIH HHS U01 HL105561NHLBI NIH HHS U01 HL105565NHLBI NIH HHS U01 HL105907
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

coronary artery diseasegerm cellsheart failuremutationrisk factors

Identifiers

PMID40207358
PMCPMC12403068

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.