Evidence map›Paper›PMID 40207269›Full record

ArticleJournal of arrhythmia2025

Clinical impact of very high-power-short-duration catheters on biomarkers after atrial fibrillation ablation.

Andrea Bernardini, Alessandro Paoletti Perini, Cristiano Salvatore Zaccaria, Davide Ciliberti, Umberto Signorini, Francesco Grossi, Raffaele Martone, Serena Fatucchi, Alenja Bertini, Anna Arretini and 5 more

Abstract read
In one paragraph

Article in Journal of arrhythmia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Andrea BernardiniCardiology and Electrophysiology Unit, Department of Medical Specialties Azienda USL Toscana Centro, Santa Maria Nuova Hospital Florence Italy.ORCID https://orcid.org/0000-0001-9732-8640
Alessandro Paoletti PeriniCardiology and Electrophysiology Unit, Department of Medical Specialties Azienda USL Toscana Centro, Santa Maria Nuova Hospital Florence Italy.
Cristiano Salvatore ZaccariaDepartment of Experimental and Clinical Medicine University of Florence Florence Italy.
Davide CilibertiDepartment of Experimental and Clinical Medicine University of Florence Florence Italy.
Umberto SignoriniCardiology and Electrophysiology Unit, Department of Medical Specialties Azienda USL Toscana Centro, Santa Maria Nuova Hospital Florence Italy.
Francesco GrossiCardiology and Electrophysiology Unit, Department of Medical Specialties Azienda USL Toscana Centro, Santa Maria Nuova Hospital Florence Italy.
Raffaele MartoneCardiology and Electrophysiology Unit, Department of Medical Specialties Azienda USL Toscana Centro, Santa Maria Nuova Hospital Florence Italy.
Serena FatucchiCardiology and Electrophysiology Unit, Department of Medical Specialties Azienda USL Toscana Centro, Santa Maria Nuova Hospital Florence Italy.
Alenja BertiniCardiology and Electrophysiology Unit, Department of Medical Specialties Azienda USL Toscana Centro, Santa Maria Nuova Hospital Florence Italy.
Anna ArretiniCardiology and Electrophysiology Unit, Department of Medical Specialties Azienda USL Toscana Centro, Santa Maria Nuova Hospital Florence Italy.
Lisa InnocentiCardiology and Electrophysiology Unit, Department of Medical Specialties Azienda USL Toscana Centro, Santa Maria Nuova Hospital Florence Italy.
Irene CapecchiCardiology and Electrophysiology Unit, Department of Medical Specialties Azienda USL Toscana Centro, Santa Maria Nuova Hospital Florence Italy.
Margherita PadelettiCardiology and Electrophysiology Unit, Department of Medical Specialties Azienda USL Toscana Centro, Santa Maria Nuova Hospital Florence Italy.
Massimo MilliCardiology and Electrophysiology Unit, Department of Medical Specialties Azienda USL Toscana Centro, Santa Maria Nuova Hospital Florence Italy.
Andrea GiomiCardiology and Electrophysiology Unit, Department of Medical Specialties Azienda USL Toscana Centro, Santa Maria Nuova Hospital Florence Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Very high-power short-duration (vHPSD) catheters are associated with less irrigation fluid load than standard (STD RF) ablation catheters. However, the impact of this fluid reduction on biomarkers in pulmonary vein isolation (PVI) for atrial fibrillation (AF) remains unknown. Methods and Aim: Biomarkers of heart failure, myocardial injury, and systemic inflammation status as Brain Natriuretic Peptide (BNP), high-sensitivity Troponin I (hsTnI), and C-reactive protein (CRP) were collected pre- and post-procedure of PVI for symptomatic AF. The study aimed to assess the impact of vHPSD catheter compared to an STD catheter (respectively irrigation of 8 vs. 15 mL/min during ablation) on biomarker alterations. Results: The study included 83 consecutive patients (59 males [71.1%], mean age 62.6 ± 11 years), with vHPSD catheters used in 53 cases (63.9%). No significant baseline differences were observed between groups.Fluid irrigation resulted in significantly lower with vHPSD catheter than STD RF (434.8 ± 105.6 vs. 806.6 ± 256.5 mL, Conclusion: The use of a vHPSD catheter is associated with reduced fluid irrigation and a correspondingly smaller increase in BNP, a biomarker indicative of fluid overload and heart failure.

Indexed as

atrial fibrillationBNPpulmonary vein isolationradiofrequencyvHPSD

Identifiers

PMID40207269
PMCPMC11980087

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.