Evidence map›Paper›PMID 40207252›Full record

ArticleNew genetics and society2024

Human Heritable Genome Editing and its Governance: Views of Scientists and Governance Professionals.

R Jean Cadigan, Margaret Waltz, John M Conley, Rami M Major, Elizabeth K Branch, Eric T Juengst, Michael A Flatt

Abstract read
In one paragraph

Article in New genetics and society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

R Jean CadiganDepartment of Social Medicine, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0002-6793-2174
Margaret WaltzDepartment of Social Medicine, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA.
John M ConleySchool of Law, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA.
Rami M MajorCurriculum in Genetics and Molecular Biology, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA.
Elizabeth K BranchSchool of Medicine, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA.
Eric T JuengstDepartment of Social Medicine, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA.
Michael A FlattDepartment of Sociology, Cuyahoga Community College, Cleveland, OH 44115, USA.

Funding

Incidental Enhancement: Addressing a Neglected Policy Issue in Human Genome EditingR01HG010661 · NHGRI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CADIGAN, ROSEMARY JEAN · 2020 to 2023
$3.1M
NHGRI NIH HHS R01 HG010661
6 · The paper itself

Abstract

Heritable human genome editing has garnered significant attention in scholarly and lay media, yet questions remain about whether, when, and how heritable genome editing ought to proceed. Drawing on interviews with scientists who use genome editing in their research and professionals engaged in human genome editing governance efforts, we examine their views on the permissibility of heritable genome editing and the governance strategies they see as necessary and realistic. For both issues, we found divergent views from respondents. We place the views of these scientists and governance professionals within the context of the larger bioethical discussion of heritable genome editing governance, along a continuum of hard to soft approaches. These respondents' views highlight the challenges of various hard forms of governance and the potential virtues of soft governance approaches.

Indexed as

governanceheritable genome editinginterviewsqualitative methodsscientists

Identifiers

PMID40207252
PMCPMC11981556

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.