Evidence map›Paper›PMID 40207137›Full record

ArticleF1000Research2024

Carbapenem-resistant Enterobacterales (CRE) in Indonesia: protocol for systematic review and meta-analysis.

Ika N Kadariswantiningsih, Maulana A Empitu, Bulat Idrisov, Derren David Christian Homenta Rampengan, Roy Novri Ramadhan

Abstract read
In one paragraph

Article in F1000Research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ika N KadariswantiningsihClinical Microbiology Residency Program, Dr. Soetomo Regional Hospital/ Faculty of Medicine, Airlangga University, Surabaya, East Java, Indonesia.ORCID https://orcid.org/0000-0001-5949-252X
Maulana A EmpituFaculty of Health, Medicine and Natural Sciences (FIKKIA), Airlangga University, Banyuwangi, East Java, Indonesia.
Bulat IdrisovHealth Services Research Department of Health Systems and Population Health, University of Washington, Seattle, Washington, USA.
Derren David Christian Homenta RampenganFaculty of Medicine, Universitas Sam Ratulangi, Manado, North Sulawesi, Indonesia.
Roy Novri RamadhanFaculty of Medicine, Airlangga University, Surabaya, East Java, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Carbapenem-resistant Enterobacterales (CRE) pose a significant global health threat, with increasing prevalence worldwide, including in Indonesia. Despite the public health impact, comprehensive data on the burden of CRE in Indonesia remains fragmented. This protocol outlines a systematic review and meta-analysis aiming to estimate the prevalence of CRE in Indonesia, summarize trends over time, and identify key resistance mechanisms. Methods: We will conduct a systematic search across multiple electronic databases, including PubMed, Scopus, and local Indonesian databases, for studies reporting the prevalence of CRE in Indonesia from 2004 to 2024. Eligibility criteria include observational studies (cross-sectional, cohort, and case-control) and surveillance reports. Data extraction will focus on CRE prevalence, bacterial species, sample types, resistance mechanisms, and study settings (hospital vs. community). Quality assessment of studies will be performed using the Newcastle-Ottawa Scale (NOS). Meta-analysis will be conducted using a random-effects model to estimate pooled prevalence, and subgroup analysis will explore variations by geographical region, period, and healthcare setting. Discussion: This systematic review and meta-analysis will provide the first comprehensive overview of CRE prevalence in Indonesia, contributing to an improved understanding of the national burden and resistance patterns. The findings will guide public health policies and inform antimicrobial stewardship efforts in Indonesia. Registration: PROSPERO CRD42024580177.

Indexed as

Carbapenem-Resistant EnterobacteriaceaeCarbapenemsEnterobacteriaceae InfectionsAnti-Bacterial AgentsHumansIndonesiaMeta-Analysis as TopicPrevalenceSystematic Reviews as TopicAnti-Bacterial AgentsCarbapenemsantimicrobial resistanceCarbapenem-resistant EnterobacteralesCREIndonesiainfectious diseaseprevalence

Identifiers

PMID40207137
PMCPMC11979575

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.