Evidence map›Paper›PMID 40207055›Full record

ArticleFrontiers in cellular and infection microbiology2025

Carbapenem-resistant

Xia Ran, Xue Chen, Cai Wang, Haiping Wang, Wei Xie, Chunmei Jing

Abstract readMulticenter Study
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Clinical risk factors and genomic characterization of carbapenem-resistantFrontiers in cellular and infection microbiology · 2026
    Article
  5. Risk factors for quinolone-resistantFrontiers in pediatrics · 2026
    Article
  6. Widespread Distribution of Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2025
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xia Ran *Department of Clinical Laboratory, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity, Chongqing, China.
Xue Chen *Department of Clinical Laboratory, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity, Chongqing, China.
Cai Wang *Department of Clinical Laboratory, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity, Chongqing, China.
Haiping WangDepartment of Clinical Laboratory, Kunming Children's Hospital, Kunming, China.
Wei XieDepartment of Clinical Laboratory, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity, Chongqing, China.
Chunmei JingDepartment of Clinical Laboratory, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study assessed epidemiology characteristics, carbapenem-resistance genes, and drug resistance to ceftazidime-avibactam (CZA) and aztreonam-avibactam (AZA) in children with carbapenem-resistant Methods: A total of 363 non-repetitive CRKP strains were collected from children who underwent two tertiary children's hospital between 1 January 2021 and 30 June 2024 in Chongqing and Kunming in Southwest China. Carbapenem resistance genes and antimicrobial susceptibility were analyzed. Basic clinical characteristics of the patients were obtained from medical records. Results: bla Conclusions: The epidemiological characteristics of Chinese children with CRKP infections, including the resistance genes and the antibiotic resistance of CRKP, exhibited significant variation between the two regions.KPC-KP strains had higher antimicrobial resistance in patients and thus should be given more attention in clinics and infection control.

Indexed as

Anti-Bacterial AgentsAzabicyclo CompoundsAztreonambeta-LactamasesCarbapenem-Resistant EnterobacteriaceaeCeftazidimeKlebsiella InfectionsKlebsiella pneumoniaeAdolescentBacterial ProteinsCarbapenemsChildChild, PreschoolChinaDrug CombinationsDrug Resistance, Multiple, BacterialAnti-Bacterial Agentsavibactam, ceftazidime drug combinationAzabicyclo CompoundsAztreonamBacterial Proteinsbeta-LactamasescarbapenemaseCarbapenemsCeftazidimeDrug Combinationsaztreonam-avibactamcarbapenem-resistant Klebsiella pneumoniaeceftazidime-avibactamepidemiology characteristicsKPC-2NDM-1 and NDM-5pediatric patient

Identifiers

PMID40207055
PMCPMC11979245

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.