ReviewMayo Clinic proceedings. Digital health2025
Clinical Applications of Fractional Flow Reserve Derived from Computed Tomography in Coronary Artery Disease.
Review in Mayo Clinic proceedings. Digital health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Diagnostic performance of CT-derived fractional flow reserve across coronary lesion morphologies: a prospective multicenter study.The international journal of cardiovascular imaging · 2026Article
- Clinical Impact of CT-Based FFR in Everyday Cardiology: Bridging Computation and Decision-Making.Biomedicines · 2025Review
- Computed Tomography and Coronary Plaque Analysis.Tomography (Ann Arbor, Mich.) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Computer tomography-derived fractional flow reserve (CT-FFR) represents a significant advancement in noninvasive cardiac functional assessment. This technology uses computer simulation and anatomical information from computer tomography of coronary angiogram to calculate the CT-FFR value at each point within the coronary vasculature. These values serve as a critical reference for cardiologists in making informed treatment decisions and planning. Emerging evidence suggests that CT-FFR has the potential to enhance the specificity of computer tomography of coronary angiogram, thereby reducing the need for additional diagnostic examinations such as invasive coronary angiography and cardiac magnetic resonance imaging. This could result in savings in financial cost, time, and resources for both patients and health care providers. However, it is important to note that although CT-FFR holds great promise, there are limitations to this technology. Users should be cautious of common pitfalls associated with its use. A comprehensive understanding of these limitations is essential for effectively applying CT-FFR in clinical practice.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.