Evidence map›Paper›PMID 40206880›Full record

ReviewFrontiers in plant science2025

Multidimensional regulation of transcription factors: decoding the comprehensive signals of plant secondary metabolism.

Hongwei Li, Nana Chen, Hongbin Zhang, Delin Xu

Abstract readReview
In one paragraph

Review in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Secondary Metabolites in Plants.Plants (Basel, Switzerland) · 2025
    Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hongwei LiDepartment of Medical Instrumental Analysis, Zunyi Medical University, Zunyi, Guizhou, China.
Nana ChenDepartment of Cell Biology, Zunyi Medical University, Zunyi, Guizhou, China.
Hongbin ZhangDepartment of Soil and Crop Sciences, Texas A&M University, College Station, TX, United States.
Delin XuDepartment of Medical Instrumental Analysis, Zunyi Medical University, Zunyi, Guizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants synthesize an extensive array of secondary metabolites in response to diverse biotic and abiotic stresses. These metabolites function not only as defensive compounds but also constitute significant sources of nutrition and pharmaceuticals. However, the mechanisms governing the synthesis of these secondary metabolites have long been a central focus of research and continue to pose significant challenges. Transcription factors (TFs), serving as key regulators of secondary metabolite synthesis in plants, exhibit mechanisms of action that are still not fully understood. This review summarizes the latest research advancements on how plant transcription factors mediate the regulation of secondary metabolite biosynthesis through various signaling pathways, including light signaling, hormone signaling, MAPK signaling, the ubiquitin-proteasome pathway, epigenetic regulation, microbial interactions, and climate change. A deeper understanding of the mechanisms regulating transcription factors is expected to provide new insights into the biosynthesis of plant secondary metabolites.

Indexed as

biosynthesismechanismssecondary metabolitessignaling pathwaystranscription factors

Identifiers

PMID40206880
PMCPMC11979206

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.