Evidence map›Paper›PMID 40206862›Full record

ArticleRoyal Society open science2025

Effectiveness of cholinium amino acid ionic liquids for the extraction of phytonutrients from palm oil.

S Y Chong, K Y Khaw, R F S Lee

Abstract read
In one paragraph

Article in Royal Society open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

S Y ChongSchool of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor 47500, Malaysia.ORCID https://orcid.org/0000-0002-3663-0106
K Y KhawSchool of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor 47500, Malaysia.
R F S LeeSchool of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor 47500, Malaysia.ORCID https://orcid.org/0000-0002-6936-0368

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Palm oil is the most widely consumed vegetable oil globally, owing to its high yield and cost-effectiveness. Beyond its primary use, palm oil is rich in valuable phytonutrients such as tocols (tocopherols and tocotrienols) and carotenoids, which hold significant economic value. Solvent extraction is a promising method to recover phytonutrients from palm oil; however, the use of flammable and toxic organic solvents raises concerns about environmental sustainability and infrastructure costs, necessitating the development of safer and more efficient solvent systems. This study investigates the potential of ionic liquids (ILs), specifically cholinium (CH) amino acid (AA) ILs ([CH][AA] ILs), as environmentally friendly and biocompatible solvents for extracting tocols and β-carotene from crude palm oil. Six [CH][AA] ILs, derived from alanine, serine, proline, glycine, leucine and lysine, were synthesized and evaluated for their extraction efficiency. Most of these ILs demonstrated significant efficacy in extracting tocotrienols and tocopherols, with the lysine-based IL showing the highest performance, extracting over 200 mg kg⁻¹. In terms of extraction efficiency, the ILs ranked as follows: lysine > proline > glycine > serine > leucine > methanol (not an IL) > alanine. Notably, none of the [CH][AA] ILs were able to extract β-carotene, highlighting their selectivity for tocols.

Indexed as

functional foodionic liquidspalm oiltocopheroltocotrienolvitamin E

Identifiers

PMID40206862
PMCPMC11979294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.