ArticleFrontiers in bioengineering and biotechnology2025
New insights into chronic ankle instability: an
Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Effects of thickness and Young's modulus of lateral ankle ligaments on ankle joint stability: a finite element study.Medical & biological engineering & computing · 2026Article
- Chronic anterior talofibular ligament rupture is associated with bilateral knee alterations and reduced ankle plantar flexor moment during gait.Frontiers in sports and active living · 2026Article
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Authors and funding
9 authors.
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Abstract
Introduction: Chronic ankle instability (CAI) is generally associated with repetitive ankle sprains with concomitant ligament injuries and abnormal joint motion, which affects the stability of the joint. This study aims to quantify and compare the 3D motion differences in the ankle joint complex (AJC) during walking between CAI patients and healthy controls and to analyze the effect of CAI on the vertical ground reaction force (vGRF) and center of pressure (COP) distribution. Methods: Fifteen CAI patients (6 males, 9 females; height 165 ± 3.8 cm; weight 68.5 ± 10.2 kg; BMI 21.6 ± 3.5 kg/m Results: Compared to controls, CAI patients showed increased plantarflexion (1.3°), internal rotation (2.0°), and medial translation (0.6 mm) in the tibiotalar joint, along with decreased dorsiflexion (3.0°). For the subtalar joint, plantarflexion decreased (1.8°), and external rotation increased (0.9°). The tibio-calcaneal joint showed increased internal rotation (1.9°) and posterior translation (0.5 mm). Stability differences included more dispersed axes of rotation and greater spatial motion volumes of landmarks in the CAI group. Additionally, CAI patients exhibited greater peak vGRF with earlier peaks, higher loading rates, and more lateral and unstable COP trajectories. Conclusion: These findings reveal that CAI not only alters the 3D motion and stability of the AJC but also affects foot-ground interaction forces, such as vGRF and COP distribution, during walking. This study provides critical insights into the altered biomechanics of the AJC in CAI patients and contributes to the clinical diagnosis of CAI and evaluation of results from surgical or conservative intervention.
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