Evidence map›Paper›PMID 40206737›Full record

ArticleSurgical neurology international2025

Intradural extramedullary eosinophilic granuloma of the spine with emergency presentation: A case report.

Wamedh Esam Matti, Hussain J Kadhum, Ibtisam Hussein Al Obaidi, Maher Khashea Mustafa, Ahmed Maan Taha Mustafa, Rasha Alaa Alshakarchy, Mustafa Ismail

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In one paragraph

Article in Surgical neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Wamedh Esam MattiDepartment of Neurosurgery, Neuroscience Hospital, Baghdad, Iraq.
Hussain J KadhumDepartment of Neurosurgery, Neuroscience Hospital, Baghdad, Iraq.
Ibtisam Hussein Al ObaidiMedical City, Teaching Labs National Center, Baghdad, Iraq.
Maher Khashea MustafaDepartment of Neurosurgery, Fallujah Teaching Hospital, Anbar, Iraq.
Ahmed Maan Taha MustafaDepartment of Neurosurgery, Neuroscience Hospital, Baghdad, Iraq.
Rasha Alaa AlshakarchyDepartment of Neurosurgery, Ghazi Alhariri Hospital, Baghdad, Iraq.
Mustafa IsmailDepartment of Neurosurgery, Medical University of South Carolina, Charleston, SC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Intradural extramedullary spinal eosinophilic granuloma is a very unusual manifestation of Langerhans Cell Histiocytosis (LCH) that is typically misdiagnosed due to its nonspecific clinical and radiological features. Case Description: We report a case of a 22-year-old female patient who presented with acute onset paraplegia. The magnetic resonance imaging was initially suggestive of tuberculoma, which is prevalent in tuberculosis-endemic regions. Intraoperative findings and histopathology, however, established the diagnosis of LCH. The lesion was intradural, and CD1a and S-100 protein staining demonstrated classic Langerhans cells. Conclusion: The paper stresses the need for a multidisciplinary team in the proper diagnosis and handling of spinal LCH. Further research is needed to develop optimal management protocols for this rare condition.

Indexed as

Histopathological diagnosisIntradural extramedullary eosinophilic granulomaLangerhans cell histiocytosisSpinal lesionTuberculoma

Identifiers

PMID40206737
PMCPMC11980720

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