ArticleData in brief2025
Proliferation and gene expression data of rabbit Achilles tenocyte in vitro culture in the presence of high-molecular weight hyaluronic acid (1.01-1.8 MDa).
Article in Data in brief, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Hyaluronic acid (HA) is a natural bio macromolecule and a good bio lubricant. As it is a predominant component of the synovial fluid, the aim was to explore the effects HA on rabbit Achilles tenocytes in vitro. The data set presents proliferation assessed by the Alamar Blue® assay; and gene expression of tenocytes that were cultured either with or without supplementation of high-molecular weight HA in a concentration of 1.4 mg/mL. There was a daily medium exchange with fresh HA supplementation. On days 3, 7 and 14 the following target genes were analysed and manifold induction was calculated against the control (no HA): Biglycan, Decorin, Aggrecan, Collagen 1A1, Collagen 1A2, Collagen 3, LOX, IL-6, TNF-α, PAR-2, ALOX-15, Tenascin-C, Tenomodulin, Mohawk, α-SMA, TIMP-1, MMP-2, MMP-9, and ki67. These data might be interesting for researchers working in the tendon field.
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