Evidence map›Paper›PMID 40206684›Full record

ArticleMayo Clinic proceedings. Digital health2024

An Automated Approach for Diagnosing Allergic Contact Dermatitis Using Deep Learning to Support Democratization of Patch Testing.

Matthew R Hall, Alexander D Weston, Mikolaj A Wieczorek, Misty M Hobbs, Maria A Caruso, Habeeba Siddiqui, Laura M Pacheco-Spann, Johanny L Lopez-Dominguez, Coralle Escoda-Diaz, Rickey E Carter and 1 more

Abstract read
In one paragraph

Article in Mayo Clinic proceedings. Digital health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Matthew R HallDepartment of Dermatology, Mayo Clinic, Jacksonville, FL.
Alexander D WestonDepartment of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL.
Mikolaj A WieczorekDepartment of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL.
Misty M HobbsDepartment of Dermatology, Mayo Clinic School of Graduate Medical Education, Mayo Clinic College of Medicine and Science, Jacksonville, FL.
Maria A CarusoDepartment of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL.
Habeeba SiddiquiDepartment of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL.
Laura M Pacheco-SpannDepartment of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL.
Johanny L Lopez-DominguezDepartment of Dermatology, Mayo Clinic, Jacksonville, FL.
Coralle Escoda-DiazUniversity of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico.
Rickey E CarterDepartment of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL.
Charles J BruceDepartment of Cardiovascular Medicine, Mayo Clinic, Jacksonville, FL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To develop a deep learning algorithm for the analysis of patch testing. Patients and Methods: A retrospective case series between January 1, 2010, and December 31, 2020, was constructed to develop a deep learning model for the classification of patch test results from photographs. The performance of human expert readers reviewing the same photographs blinded to the original clinical physical examination findings was measured to benchmark model performance. Results: Model performance on the independent test set (n=5070 test site locations from 37 patients) achieved an area under the receiver operating characteristic curve of 0.89 (95% CI, 0.86-0.91) and an F1 score of 37.1. The optimal cutoff had a sensitivity of 70.1% (136/194; 95% CI, 63.1%-76.5%) and a specificity of 91.7% (4472/4876; 95% CI, 90.9%-92.5%). Conclusion: We demonstrated proof-of-concept utility for detecting allergic contact dermatitis using an automated deep learning approach.

Identifiers

PMID40206684
PMCPMC11975759

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.