Evidence map›Paper›PMID 40206651›Full record

ArticleFrontiers in psychiatry2025

Improvement of alexithymia in patients treated in mental health services for personality disorders: a longitudinal, observational study.

Hanna Sayar, Theresa Wilberg, Ingeborg Ulltveit-Moe Eikenæs, Andreas Ekberg, Kai Leitemo, Katharina Teresa Enehaug Morken, Eileen Oftedal, Siri Omvik, Dag Anders Ulvestad, Geir Pedersen and 1 more

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hanna SayarDepartment of Psychology, Faculty of Social Sciences, University of Oslo, Oslo, Norway.
Theresa WilbergInstitute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Ingeborg Ulltveit-Moe EikenæsDepartment of Addiction Treatment, Division Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Andreas EkbergDepartment of Addiction Treatment, Division Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Kai LeitemoSection for Group Therapy, Lovisenberg Diaconal Hospital, Oslo, Norway.
Katharina Teresa Enehaug MorkenDepartment of Addiction Medicine, Haukeland University Hospital, Bergen, Norway.
Eileen OftedalGroup Outpatient Clinic, Stavanger District Psychiatric Center, Division of Adult Mental Health Care, Stavanger University Hospital, Stavanger, Norway.
Siri OmvikDepartment of Welfare and Participation, Western Norway University of Applied Sciences, Bergen, Norway.
Dag Anders UlvestadInstitute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Geir PedersenDepartment of Research and Innovation, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Elfrida Hartveit KvarsteinInstitute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The majority of mental health services include patients with personality disorder (PD) and comorbid conditions. Alexithymia, a psychological construct referring to difficulties in identifying and describing internal mental states, may represent a challenge to the psychotherapeutic treatment of patients with PD. This study aimed to investigate the prevalence of alexithymia among patients in specialized PD mental health services, differences according to PD severity and PD type, and the longitudinal course of alexithymia during treatment. Methods: The study included 1,019 patients treated in specialized PD treatment units, with 70% of them with personality difficulties above the PD diagnostic threshold [borderline PD, 31%; avoidant PD, 39%; PD not otherwise specified (PD-NOS), 15%; other PDs, 15%; and more than one PD, 24%]. Alexithymia was measured repeatedly throughout treatment using the Toronto Alexithymia Scale (TAS-20) self-report questionnaire. Supplementary outcomes included global psychosocial function and health-related life quality. Linear mixed models were applied for data analysis. Results: Alexithymia was highly prevalent in the sample: 53% of subjects reported high levels and 20% moderate levels. The TAS-20 subscale Difficulty Identifying Feelings was more strongly associated with borderline PD, while the subscale Difficulty Describing Feelings was more closely linked to avoidant PD. For all TAS subscales, poorer abilities were associated with more severe PD, higher levels of anxiety and depression, and poorer psychosocial functioning and life quality. Both alexithymia and measures of psychological functioning improved significantly during treatment with moderate effect sizes regardless of initial PD status. In total, 19% of the patients reported full remission of alexithymia. Conclusion: Alexithymia is a common problem among patients with PDs and is associated with mental health difficulties and psychosocial dysfunction, with rates varying across PD type and severity. The study demonstrates moderate improvement of alexithymia during treatment in specialized PD mental health services. Further research should evaluate the effectiveness of different treatments and interventions in reducing alexithymia among PD patients.

Indexed as

alexithymiaavoidant personality disorderborderline personality disorderimprovementlongitudinalpersonality disorderstreatment

Identifiers

PMID40206651
PMCPMC11979213

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.