Evidence map›Paper›PMID 40206551›Full record

ReviewChemical science2025

Polymersome-based nanomotors: preparation, motion control, and biomedical applications.

Siyu Song, Hao Han, Jianhong Wang, Yubin Pu, Jingxin Shao, Jing Xie, Hailong Che, Jan C M van Hest, Shoupeng Cao

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Chemical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Siyu SongLife-Like Materials and Systems, Department of Chemistry, University of Mainz Mainz 55128 Germany.
Hao HanCollege of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University Chengdu 610065 PR China caoshoupeng@scu.edu.cn.
Jianhong WangBio-Organic Chemistry, Institute of Complex Molecular Systems, Eindhoven University of Technology Helix, P. O. Box 513 Eindhoven 5600 MB The Netherlands J.C.M.v.Hest@tue.nl.
Yubin PuCollege of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University Chengdu 610065 PR China caoshoupeng@scu.edu.cn.
Jingxin ShaoBio-Organic Chemistry, Institute of Complex Molecular Systems, Eindhoven University of Technology Helix, P. O. Box 513 Eindhoven 5600 MB The Netherlands J.C.M.v.Hest@tue.nl.ORCID https://orcid.org/0009-0007-8888-9172
Jing XieInstitute of Biomedical Engineering, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University Chengdu 610041 China jingxie@scu.edu.cn.
Hailong CheDepartment of Chemical Engineering, School of Environmental and Chemical Engineering, Shanghai University Shanghai 200444 China hche@shu.edu.cn.ORCID https://orcid.org/0000-0003-3945-570X
Jan C M van HestBio-Organic Chemistry, Institute of Complex Molecular Systems, Eindhoven University of Technology Helix, P. O. Box 513 Eindhoven 5600 MB The Netherlands J.C.M.v.Hest@tue.nl.ORCID https://orcid.org/0000-0001-7973-2404
Shoupeng CaoCollege of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University Chengdu 610065 PR China caoshoupeng@scu.edu.cn.ORCID https://orcid.org/0000-0002-5856-2407

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymersome-based nanomotors represent a cutting-edge development in nanomedicine, merging the unique vesicular properties of polymersomes with the active propulsion capabilities of synthetic nanomotors. As a vesicular structure enclosed by a bilayer membrane, polymersomes can encapsulate both hydrophilic and hydrophobic cargoes. In addition, their physical-chemical properties such as size, morphology, and surface chemistry are highly tunable, which makes them ideal for various biomedical applications. The integration of motility into polymersomes enables them to actively navigate biological environments and overcome physiological barriers, offering significant advantages over passive delivery platforms. Recent breakthroughs in fabrication techniques and motion control strategies, including chemically, enzymatically, and externally driven propulsion, have expanded their potential for drug delivery, biosensing, and therapeutic interventions. Despite these advancements, key challenges remain in optimizing propulsion efficiency, biocompatibility, and

Identifiers

PMID40206551
PMCPMC11976864

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.