Evidence map›Paper›PMID 40206462›Full record

ArticlemicroPublication biology2025

Filamin A interacting protein 1-like (FILIP1L) has mitochondrial localization.

Sarah Henretta, Karisa Bockley, Jacob Odell, Jan Lammerding

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in microPublication biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sarah Henretta *Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853.
Karisa Bockley *Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853.
Jacob OdellWeill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853.
Jan LammerdingMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853.

Funding

Nuclear mechanics and mechanotransduction in muscular laminopathiesR01HL082792 · NHLBI · CORNELL UNIVERSITY · PI LAMMERDING, JAN · 2007 to 2023
$4.8M
Defining nuclear mechanisms for ultrarapid mechanically induced gene expressionR01AR084664 · NIAMS · CORNELL UNIVERSITY · PI JOHN T LIS, Jan Lammerding · 2024 to 2026
$1.8M
Nuclear mechanobiology in confined migration (equipment supplement 2026)R35GM153257 · NIGMS · CORNELL UNIVERSITY · PI Jan Lammerding · 2024 to 2026
$1.3M
NHLBI NIH HHS R01 HL082792NIAMS NIH HHS R01 AR084664NIGMS NIH HHS R35 GM153257
6 · The paper itself

Abstract

Filamin A interacting protein 1-like (FILIP1L) is a multifunctional protein that plays a role in cancer progression, apoptosis, and angiogenesis. However, FILIP1L remains a relatively underexplored protein, and many of FILIP1L's key mechanisms and interacting partners are still unknown. Using immunofluorescence staining for endogenous FILIP1L and high-resolution confocal microscopy, we show that FILIP1L colocalizes with the mitochondrial marker, TOM20, suggesting a novel connection between FILIP1L and mitochondria. Further exploring the relationship between FILIP1L and mitochondria might provide a deeper understanding of the emerging function of FILIP1L in health and disease.

Identifiers

PMID40206462
PMCPMC11979717

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.