ArticleNeurophotonics2025
Beneath the surface: revealing deep-tissue blood flow in human subjects with massively parallelized diffuse correlation spectroscopy.
Article in Neurophotonics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Characterization of a fiber-coupled SPAD camera system for deep-tissue blood-flow measurement using diffuse correlation spectroscopy.Biomedical optics express · 2026Article
- Highly parallel, 1060 nm interferometric diffusing wave spectroscopy with a time-of-flight filter.Biomedical optics express · 2026Article
- SAR-Constrained Wireless Power Transfer Modeling for an Implantable Optical Neurostimulator Sensors.Sensors (Basel, Switzerland) · 2025Article
- Synthetic-data-driven LSTM framework for tracing cardiac pulsation in optical signals.Biomedical optics express · 2025Article
- Beneath the surface: revealing deep-tissue blood flow in human subjects with massively parallelized diffuse correlation spectroscopy.Neurophotonics · 2025Article
- Article
- ATLAS: a large array, on-chip compute SPAD camera for multispeckle diffuse correlation spectroscopy.Biomedical optics express · 2024Article
- Probing diffusive media through speckle differencing.Biomedical optics express · 2024Article
- Tunable dynamical tissue phantom for laser speckle imaging.Biomedical optics express · 2024Article
- Comprehensive Optimization of Interferometric Diffusing Wave Spectroscopy (iDWS).IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics SocietyArticle
- Pathlength-selective, interferometric diffuse correlation spectroscopy.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics SocietyArticle
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20 authors.
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Abstract
Significance: Diffuse correlation spectroscopy (DCS) allows label-free, non-invasive investigation of microvascular dynamics deep within tissue, such as cerebral blood flow (CBF). However, the signal-to-noise ratio (SNR) in DCS limits its effective cerebral sensitivity in adults, in which the depth to the brain, through the scalp and skull, is substantially larger than in infants. Aim: Therefore, we aim to increase its SNR and, ultimately, its sensitivity to CBF through new DCS techniques. Approach: We present an Results: The new system can measure pulsatile blood flow in cerebral and muscular tissue, at up to 4 cm SDS, while maintaining a similar measurement noise as compared with a previously published Conclusions: Our results outline successful PDCS measurements with large SPAD arrays to enable detect CBF in human adults. The ongoing development of SPAD camera technology is expected to result in larger and faster detectors in the future. In combination with new data processing techniques, tailored for the sparse signal of binary photon detection events in SPADs, this could lead to even greater SNR increase and ultimately greater depth sensitivity of PDCS.
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