Evidence map›Paper›PMID 40206366›Full record

ArticleIranian journal of parasitology

Investigating the Lethal Effects of Carvone on the Protoscoleces of Hydatid Cyst,

Hossein Mahmoudvand, Amal Khudair Khalaf, Ezatollah Fazeli Moghadam, Javad Ghasemian Yadegari, Ahmad Adineh, Amir Jalili

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In one paragraph

Article in Iranian journal of parasitology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hossein MahmoudvandRazi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
Amal Khudair KhalafDepartment of Microbiology, College of Medicine, University of Thi-qar, Thi-qar, Iraq.
Ezatollah Fazeli MoghadamNutritional Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
Javad Ghasemian YadegariDepartment of Pharmacognosy, Lorestan University of Medical Sciences, Khorramabad, Iran.
Ahmad AdinehDepartment of Toxicology, School of Pharmacy, Lorestan University of Medical Sciences, Khorramabad, Iran.
Amir JaliliStudent Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Medicinal plants and their derivatives due to having high availability, low cost, low toxicity, and high efficacy are recognized as significant reservoirs of a diverse array of valuable therapeutic compounds. We aimed to investigate the lethal effects of carvone (CV) on protoscoleces of hydatid cyst, in laboratory and Methods: The protoscolicidal effects of CV were investigated both Results: CV, particularly at a concentration of 150 μg/ml, effectively eradicated protoscoleces of hydatid cysts within a 20-minute exposure period. Furthermore, CV exhibited sustained anti-parasitic effects in the Conclusion: The findings demonstrated the potential of CV to eliminate protoscoleces by inducing apoptosis and causing DNA damage. However, further studies are required to clarify the specific mechanisms underlying its action and to assess its efficacy in clinical trials, which may facilitate the application of CV in the context of hydatid cyst surgical procedures.

Indexed as

Anti-helminthicApoptosisCarvoneHydatid cystProtoscolices

Identifiers

PMID40206366
PMCPMC11978205

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.