Evidence map›Paper›PMID 40206343›Full record

ArticleEuropean journal of anaesthesiology and intensive care2025

The in-vitro performance of a modern portable respirator in different lung models and as an alternative intensive care respirator: A simulation based cohort study.

Celine Josianne Schneider, Christian Peter Both, Daniel Fries, Pedro David Wendel-Garcia, Philipp Karl Buehler, Beate Grass, Vincenzo Cannizzaro, Christian Escher, Achim Schmitz, Jörg Thomas

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Article in European journal of anaesthesiology and intensive care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Celine Josianne SchneiderFrom the Department of Anesthesiology, Children's University Hospital Zurich, Zurich, Switzerland (CJS, CPB, DF, PKB, AS, JT), Department of Anesthesiology, Children Hospital St. Gallen, St. Gallen/Switzerland (CPB), Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland (CJS, CPB, PKB, BG, VC, AS, JT), Department of Anesthesiology, University Hospital Zurich, Zurich, Switzerland (DF, PDW-G), Institut of Intensive Care, University Hospital Zurich, Zurich, Switzerland (PDW-G), Department of Intensive Care, Hospital Winterthur, Winterthur, Switzerland (PKB), Department of Neonatal Intensive Care, University Hospital Zurich, Zurich, Switzerland (BG, VC), Department of Anesthesiology, Hospital Aarau, Aargau, Switzerland (CE), and Department of Anesthesiology, Hospital Winterthur, Winterthur, Switzerland (CJS).
Christian Peter BothFrom the Department of Anesthesiology, Children's University Hospital Zurich, Zurich, Switzerland (CJS, CPB, DF, PKB, AS, JT), Department of Anesthesiology, Children Hospital St. Gallen, St. Gallen/Switzerland (CPB), Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland (CJS, CPB, PKB, BG, VC, AS, JT), Department of Anesthesiology, University Hospital Zurich, Zurich, Switzerland (DF, PDW-G), Institut of Intensive Care, University Hospital Zurich, Zurich, Switzerland (PDW-G), Department of Intensive Care, Hospital Winterthur, Winterthur, Switzerland (PKB), Department of Neonatal Intensive Care, University Hospital Zurich, Zurich, Switzerland (BG, VC), Department of Anesthesiology, Hospital Aarau, Aargau, Switzerland (CE), and Department of Anesthesiology, Hospital Winterthur, Winterthur, Switzerland (CJS).
Daniel FriesFrom the Department of Anesthesiology, Children's University Hospital Zurich, Zurich, Switzerland (CJS, CPB, DF, PKB, AS, JT), Department of Anesthesiology, Children Hospital St. Gallen, St. Gallen/Switzerland (CPB), Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland (CJS, CPB, PKB, BG, VC, AS, JT), Department of Anesthesiology, University Hospital Zurich, Zurich, Switzerland (DF, PDW-G), Institut of Intensive Care, University Hospital Zurich, Zurich, Switzerland (PDW-G), Department of Intensive Care, Hospital Winterthur, Winterthur, Switzerland (PKB), Department of Neonatal Intensive Care, University Hospital Zurich, Zurich, Switzerland (BG, VC), Department of Anesthesiology, Hospital Aarau, Aargau, Switzerland (CE), and Department of Anesthesiology, Hospital Winterthur, Winterthur, Switzerland (CJS).
Pedro David Wendel-GarciaFrom the Department of Anesthesiology, Children's University Hospital Zurich, Zurich, Switzerland (CJS, CPB, DF, PKB, AS, JT), Department of Anesthesiology, Children Hospital St. Gallen, St. Gallen/Switzerland (CPB), Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland (CJS, CPB, PKB, BG, VC, AS, JT), Department of Anesthesiology, University Hospital Zurich, Zurich, Switzerland (DF, PDW-G), Institut of Intensive Care, University Hospital Zurich, Zurich, Switzerland (PDW-G), Department of Intensive Care, Hospital Winterthur, Winterthur, Switzerland (PKB), Department of Neonatal Intensive Care, University Hospital Zurich, Zurich, Switzerland (BG, VC), Department of Anesthesiology, Hospital Aarau, Aargau, Switzerland (CE), and Department of Anesthesiology, Hospital Winterthur, Winterthur, Switzerland (CJS).
Philipp Karl BuehlerFrom the Department of Anesthesiology, Children's University Hospital Zurich, Zurich, Switzerland (CJS, CPB, DF, PKB, AS, JT), Department of Anesthesiology, Children Hospital St. Gallen, St. Gallen/Switzerland (CPB), Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland (CJS, CPB, PKB, BG, VC, AS, JT), Department of Anesthesiology, University Hospital Zurich, Zurich, Switzerland (DF, PDW-G), Institut of Intensive Care, University Hospital Zurich, Zurich, Switzerland (PDW-G), Department of Intensive Care, Hospital Winterthur, Winterthur, Switzerland (PKB), Department of Neonatal Intensive Care, University Hospital Zurich, Zurich, Switzerland (BG, VC), Department of Anesthesiology, Hospital Aarau, Aargau, Switzerland (CE), and Department of Anesthesiology, Hospital Winterthur, Winterthur, Switzerland (CJS).
Beate GrassFrom the Department of Anesthesiology, Children's University Hospital Zurich, Zurich, Switzerland (CJS, CPB, DF, PKB, AS, JT), Department of Anesthesiology, Children Hospital St. Gallen, St. Gallen/Switzerland (CPB), Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland (CJS, CPB, PKB, BG, VC, AS, JT), Department of Anesthesiology, University Hospital Zurich, Zurich, Switzerland (DF, PDW-G), Institut of Intensive Care, University Hospital Zurich, Zurich, Switzerland (PDW-G), Department of Intensive Care, Hospital Winterthur, Winterthur, Switzerland (PKB), Department of Neonatal Intensive Care, University Hospital Zurich, Zurich, Switzerland (BG, VC), Department of Anesthesiology, Hospital Aarau, Aargau, Switzerland (CE), and Department of Anesthesiology, Hospital Winterthur, Winterthur, Switzerland (CJS).
Vincenzo CannizzaroFrom the Department of Anesthesiology, Children's University Hospital Zurich, Zurich, Switzerland (CJS, CPB, DF, PKB, AS, JT), Department of Anesthesiology, Children Hospital St. Gallen, St. Gallen/Switzerland (CPB), Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland (CJS, CPB, PKB, BG, VC, AS, JT), Department of Anesthesiology, University Hospital Zurich, Zurich, Switzerland (DF, PDW-G), Institut of Intensive Care, University Hospital Zurich, Zurich, Switzerland (PDW-G), Department of Intensive Care, Hospital Winterthur, Winterthur, Switzerland (PKB), Department of Neonatal Intensive Care, University Hospital Zurich, Zurich, Switzerland (BG, VC), Department of Anesthesiology, Hospital Aarau, Aargau, Switzerland (CE), and Department of Anesthesiology, Hospital Winterthur, Winterthur, Switzerland (CJS).
Christian EscherFrom the Department of Anesthesiology, Children's University Hospital Zurich, Zurich, Switzerland (CJS, CPB, DF, PKB, AS, JT), Department of Anesthesiology, Children Hospital St. Gallen, St. Gallen/Switzerland (CPB), Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland (CJS, CPB, PKB, BG, VC, AS, JT), Department of Anesthesiology, University Hospital Zurich, Zurich, Switzerland (DF, PDW-G), Institut of Intensive Care, University Hospital Zurich, Zurich, Switzerland (PDW-G), Department of Intensive Care, Hospital Winterthur, Winterthur, Switzerland (PKB), Department of Neonatal Intensive Care, University Hospital Zurich, Zurich, Switzerland (BG, VC), Department of Anesthesiology, Hospital Aarau, Aargau, Switzerland (CE), and Department of Anesthesiology, Hospital Winterthur, Winterthur, Switzerland (CJS).
Achim SchmitzFrom the Department of Anesthesiology, Children's University Hospital Zurich, Zurich, Switzerland (CJS, CPB, DF, PKB, AS, JT), Department of Anesthesiology, Children Hospital St. Gallen, St. Gallen/Switzerland (CPB), Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland (CJS, CPB, PKB, BG, VC, AS, JT), Department of Anesthesiology, University Hospital Zurich, Zurich, Switzerland (DF, PDW-G), Institut of Intensive Care, University Hospital Zurich, Zurich, Switzerland (PDW-G), Department of Intensive Care, Hospital Winterthur, Winterthur, Switzerland (PKB), Department of Neonatal Intensive Care, University Hospital Zurich, Zurich, Switzerland (BG, VC), Department of Anesthesiology, Hospital Aarau, Aargau, Switzerland (CE), and Department of Anesthesiology, Hospital Winterthur, Winterthur, Switzerland (CJS).
Jörg ThomasFrom the Department of Anesthesiology, Children's University Hospital Zurich, Zurich, Switzerland (CJS, CPB, DF, PKB, AS, JT), Department of Anesthesiology, Children Hospital St. Gallen, St. Gallen/Switzerland (CPB), Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland (CJS, CPB, PKB, BG, VC, AS, JT), Department of Anesthesiology, University Hospital Zurich, Zurich, Switzerland (DF, PDW-G), Institut of Intensive Care, University Hospital Zurich, Zurich, Switzerland (PDW-G), Department of Intensive Care, Hospital Winterthur, Winterthur, Switzerland (PKB), Department of Neonatal Intensive Care, University Hospital Zurich, Zurich, Switzerland (BG, VC), Department of Anesthesiology, Hospital Aarau, Aargau, Switzerland (CE), and Department of Anesthesiology, Hospital Winterthur, Winterthur, Switzerland (CJS).ORCID https://orcid.org/0000-0001-8452-356X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTransporting ventilated patients safely and without loss of efficacy is a challenge. Portable ventilators are generally used to transport critically ill patients, but their performance is often limited.

objectiveThis study aimed to compare the in-vitro performance of a modern portable respirator with a modern intensive care respirator for different lung settings.

designAn in-vitro testing of a portable and an intensive care respirator. SETTINGS: Anaesthesia Department at the University Children's Hospital Zurich.

main outcome measuresThe portable respirator Hamilton T1 was compared with the established intensive care respirator bellavista1000 (BV) while applying different settings with the ASL 5000 (ASL) device. The ASL can simulate neonatal, paediatric, and adult lung settings with normal or impaired lung function. Accuracy of delivered tidal volumes, proximal and distal airway pressures and mechanical lung properties were assessed.

resultsBland-Altman analyses showed higher accuracy for applied tidal volumes delivered by the portable respirator, 12.6% [95% confidence interval (CI) -8.9 to 34.2], compared with the intensive care respirator, 15.9% (95% CI -18.5 to 50.3). In neonatal and infant lung models particularly, the accuracy of delivered tidal volumes by the portable respirator, 13.2% (95% CI -8.9 to 35.3) was superior to those delivered by the intensive care respirator, 20.9% (95%CI -15.9 to 57.7). Lung compliance estimation was performed more accurately by the intensive care respirator, whereas the portable respirator measured airway resistance more accurately. However, both respirators showed only moderate overall accuracy when assessing lung mechanics.

conclusionThe tested portable respirator proved to be a useful device for invasive ventilation of critically ill patients. The overall performance is non-inferior to a conventional intensive care respirator.

Identifiers

PMID40206343
PMCPMC11977734

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