Evidence map›Paper›PMID 40206335›Full record

ArticleIDCases2024

A fungal nightmare: A rare and deadly presentation of disseminated histoplasmosis.

Amal Naji, Martin Baxter, Alex Kumi, Jan Camille Ozaeta, Nicole Onuoha, Danhely Cruz-Vasquez, Olawole Akinboboye, John-Paul Papadopoulos, Zola Nlandu

Abstract readCase Reports
In one paragraph

Article in IDCases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amal NajiDepartment of Internal Medicine, Piedmont Athens Regional, GA, USA.
Martin BaxterDepartment of Internal Medicine, Piedmont Athens Regional, GA, USA.
Alex KumiDepartment of Internal Medicine, Piedmont Athens Regional, GA, USA.
Jan Camille OzaetaDepartment of Internal Medicine, Piedmont Athens Regional, GA, USA.
Nicole OnuohaDepartment of Internal Medicine, Piedmont Athens Regional, GA, USA.
Danhely Cruz-VasquezDepartment of Internal Medicine, Piedmont Athens Regional, GA, USA.
Olawole AkinboboyeDepartment of Internal Medicine, Piedmont Athens Regional, GA, USA.
John-Paul PapadopoulosDepartment of Internal Medicine, Piedmont Athens Regional, GA, USA.
Zola NlanduDepartment of Internal Medicine, Piedmont Athens Regional, GA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Histoplasma capsulatum is a dimorphic fungus commonly associated with localized pulmonary disease but can often spread to various organs causing disseminated histoplasmosis. Once the disseminated disease reaches the central nervous system (CNS), mortality rates increase significantly and can reach up to 40 %. The prognosis is frequently determined by adequate and timely diagnosis. Treatment often includes amphotericin B for a total of 4-6 weeks followed by itraconazole for at least 1 year. Herein, we present the case of a 65-year-old male who initially presented with worsening headaches and was later found to have disseminated histoplasmosis.

Indexed as

FungiHeart transplantHistoplasmaImmunosuppressed

Identifiers

PMID40206335
PMCPMC11980627

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.