Evidence map›Paper›PMID 40206207›Full record

ArticleJournal of clinical imaging science2025

Efficacy of dual-layer spectral detector computed tomography for detecting early ischemic changes in patients with acute ischemic stroke: A pilot study.

Keiichi Honda, Seitaro Oda, Daisuke Kondo, Ryusuke Kujirai, Ko Higuchi, Takumi Osaki, Akiko Sugisaki, Naoya Moriguchi, Ryo Akagi, Toshinori Hirai and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical imaging science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Keiichi HondaDepartment of Radiological Technology, Kumamoto University, Kumamoto, Japan.
Seitaro OdaDepartment of Diagnostic Radiology, Kumamoto University, Kumamoto, Japan.
Daisuke KondoDepartment of Radiological Technology, Kumamoto University, Kumamoto, Japan.
Ryusuke KujiraiDepartment of CT Clinical Science, Philips Japan, Tokyo, Japan.
Ko HiguchiDepartment of CT Clinical Science, Philips Japan, Tokyo, Japan.
Takumi OsakiDepartment of Diagnostic Radiology, Kumamoto University, Kumamoto, Japan.
Akiko SugisakiDepartment of Diagnostic Radiology, Kumamoto University, Kumamoto, Japan.
Naoya MoriguchiDepartment of Diagnostic Radiology, Kumamoto University, Kumamoto, Japan.
Ryo AkagiDepartment of Diagnostic Radiology, Kumamoto University, Kumamoto, Japan.
Toshinori HiraiDepartment of Diagnostic Radiology, Kumamoto University, Kumamoto, Japan.
Kazuhiro KatahiraDiagnostic Radiology, Kumamoto Chuo Hospital, Kumamoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study evaluated the efficacy of dual-layer spectral detector computed tomography (DLCT) for detecting early ischemic changes (EICs) in patients with acute ischemic stroke (AIS), focusing on electron density (ED) and effective atomic number (effective Z) imaging. Material and Methods: This retrospective study included 15 patients (mean age: 76.5 ± 9.8 years) with AIS who underwent non-contrast computed tomography (CT) with DLCT and magnetic resonance imaging (MRI) on the same day. Quantitative analysis was performed to compare conventional CT, ED, and effective Z values between the infarcted and contralateral brain regions. Qualitative assessment was conducted by two radiologists using the modified Alberta Stroke Program Early CT Score methodology. Receiver operating characteristic curve analysis was performed to evaluate diagnostic performance, and kappa statistics were used to assess interobserver agreement. Results: Significant differences were observed in the conventional CT and ED values ( Conclusion: Compared with conventional CT, DLCT with ED imaging significantly enhanced detection of EICs in AIS.

Indexed as

Area under curveBrainElectronsIschemic strokeTomography

Identifiers

PMID40206207
PMCPMC11980743

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.