ArticleCyborg and bionic systems (Washington, D.C.)2025
Noninvasive Intracranial Source Signal Localization and Decoding with High Spatiotemporal Resolution.
Article in Cyborg and bionic systems (Washington, D.C.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Online Signal-to-Noise Management for Evoked Potentials-Assessing and Explaining Response Quality.Bioengineering (Basel, Switzerland) · 2026Article
- Low-intensity transcranial focused ultrasound engages parvalbumin-positive GABAergic interneurons in a humanized mouse model of chronic pain: from electrophysiology to cellular investigation.Journal of neural engineering · 2026Article
- The mouse motor cortex stimulation via non-invasive temporal interference transcranial focused ultrasound with microbubbles.Ultrasonics sonochemistry · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High spatiotemporal resolution of noninvasive electroencephalography (EEG) signals is an important prerequisite for fine brain-computer manipulation. However, conventional scalp EEG has a low spatial resolution due to the volume conductor effect, making it difficult to accurately identify the intent of brain-computer manipulation. In recent years, transcranial focused ultrasound modulated EEG technology has increasingly become a research hotspot, which is expected to acquire noninvasive acoustoelectric coupling signals with a high spatial and temporal resolution. In view of this, this study established a transcranial focused ultrasound numerical simulation model and experimental platform based on a real brain model and a 128-array phased array, further constructed a 3-dimensional transcranial multisource dipole localization and decoding numerical simulation model and experimental platform based on the acoustic field platform, and developed a high-precision localization and decoding algorithm. The results show that the simulation-guided phased-array acoustic field experimental platform can achieve accurate focusing in both pure water and transcranial conditions within a safe threshold, with a modulation range of 10 mm, and the focal acoustic pressure can be enhanced by more than 200% compared with that of transducer self-focusing. In terms of dipole localization decoding results, the proposed algorithm in this study has a localization signal-to-noise ratio of 24.18 dB, which is 50.59% higher than that of the traditional algorithm, and the source signal decoding accuracy is greater than 0.85. This study provides a reliable experimental basis and technical support for high-spatiotemporal-resolution noninvasive EEG signal acquisition and precise brain-computer manipulation.
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Registered trials
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