ReviewFrontiers in pharmacology2025
Selected traditional Chinese herbal medicines for the treatment of atopic dermatitis - research progress on the effect and mechanism of actions.
Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Efficacy and Safety of Integrated Traditional Chinese Medicine and Biologic Treatment in Moderate to Severe Atopic Dermatitis: Protocol for a Prospective Observational Real-World Study.JMIR research protocols · 2026Article
- Yin-Hua Li-Shi Formula Exerts Anti-Atopic Dermatitis Effects Through Luteolin Targeting AKT/MAPK-IL-6/IL-17 Axis.Journal of inflammation research · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atopic dermatitis (AD) is a common chronic, recurrent, inflammatory skin disease characterized by pruritus, lichen-like changes and dry skin. Due to the complex pathogenesis of AD, its mechanism is primarily associated with genetic, skin barrier dysfunction, environmental, and immune factors. AD has been routinely treated with glucocorticoids, antihistamines, local immunomodulators, biological agents, and small molecules; however, the side effects are significant, and the treatment efficacy is limited. In recent years, traditional Chinese medicine (TCM) has gradually been widely used in the treatment of AD. Many studies have shown that TCM mainly regulates inflammatory cytokines, gut microbiota and the immune system. Therefore, it plays a crucial role in the treatment of AD. The treatment of atopic dermatitis using TCM is characterized by targeting multiple pathways and multiple targets, and it demonstrates significant therapeutic effects. This paper reviews the pathogenesis of AD and reports the efficacy of TCM on AD (including TCM prescription, single TCM, treatment of TCM metabolites), which provides a theoretical basis for TCM treatment of AD. TCM has certain therapeutic effects on AD. It can alleviate and treat AD in various ways. We should base our differentiation on syndrome differentiation and treatment differentiation. With the help of modern medicine, the clinical efficacy of TCM in treating AD can be improved.
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Registered trials
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