Evidence map›Paper›PMID 40206056›Full record

ArticleFrontiers in pharmacology2025

An analysis of the clinical application of paliperidone palmitate injection based on real-world.

Ruixue Liu, Chunxiao Liu, Di Hu, Longkun Wang, Dianwei Feng, Tongxin Guo, Ying Wang

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ruixue Liu *Department of Pharmacy, Tianjin Anding Hospital, Tianjin, China.
Chunxiao Liu *Department of Pharmacy, Tianjin Anding Hospital, Tianjin, China.
Di HuDepartment of Pharmacy, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin, China.
Longkun WangDepartment of Pharmacy, Tianjin Anding Hospital, Tianjin, China.
Dianwei FengDepartment of Pharmacy, Tianjin Anding Hospital, Tianjin, China.
Tongxin GuoDepartment of Pharmacy, Tianjin Anding Hospital, Tianjin, China.
Ying WangDepartment of Pharmacy, Tianjin Anding Hospital, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To analyze the clinical application, adherence and relapse of paliperidone palmitate (PP) injection. Method: The information of patients treated with PP 1-month (PP1M), patients switching from PP1M to paliperidone palmitate 3-month (PP3M), and the relapse of patients after discharge from 1 January 2021 to 31 December 2023 was retrieved from the electronic medical record system. Descriptive statistics, two-tailed Results: 189 patients were administered with PP1M in this study accounted for 0.88% of all inpatients. 5 (9.09%) patients were switched from risperidone long-acting injection (RLAI) to PP1M. 45 (∼23.81%) patients were switched into PP3M. The patients without relapses were twice than relapsed patients after discharge of 1 year. Patients with initial episodes administered with PP1M showed fewer relapses than patients with non-initial episodes (11.11% vs. 34.72%; Conclusion: The current utilization of PP1M and conversion from PP1M to PP3M is low. Patients with initial episodes with and adhering to PP injection were at lower risk of relapse. Thus, the patients' adherence and the education about PP injections should be improved.

Indexed as

long-acting injectable antipsychoticspaliperidone palmitatepaliperidone palmitate 1-monthpaliperidone palmitate 3-monthschizophrenia

Identifiers

PMID40206056
PMCPMC11978662

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.