Evidence map›Paper›PMID 40206031›Full record

ReviewFrontiers in molecular biosciences2025

Global knowledge mapping of receptor activator of nuclear factor kappa-B ligand in osteoporotic fractures: a bibliometric analysis (2001-2024).

Shuai Lu, Huaishuang Shen, Minjuan Li, Yiming Luo, Hao Sun, Xian Zhao, Jianming Chen, Ruifeng Bai, Pengli Han, Yejun Zha and 1 more

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PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in molecular biosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shuai Lu *Department of Orthopedic Trauma, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Huaishuang Shen *Department of Orthopaedic Surgery, First Affiliated Hospital of Soochow University, Suzhou, China.
Minjuan LiDepartment of Orthopedic Trauma, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Yiming LuoGeriatric Orthopedic, Shenzhen Pingle Orthopedic Hospital (Shenzhen Pingshan Traditional Chinese Medicine Hospital), Shenzhen, China.
Hao Sun *Department of Orthopedic Trauma, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Xian ZhaoDepartment of Orthopedic Trauma, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Jianming ChenDepartment of orthopedic, People's Hospital of Lingcheng District, Dezhou, China.
Ruifeng BaiDepartment of Clinical Laboratory, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Pengli HanPharmaceutical Department, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China.
Yejun ZhaDepartment of Orthopedic Trauma, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Xieyuan JiangDepartment of Orthopedic Trauma, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Receptor activator of nuclear factor kappa-B ligand (RANKL) plays a critical role in bone metabolism and the pathogenesis of osteoporotic fractures. This study aims to conduct a bibliometric analysis of global research pertaining to RANKL and osteoporotic fractures to identify key trends, influential studies, and collaborative networks. Methods: A literature search was conducted to identify articles found in the Web of Science Core Collection database regarding RANKL and osteoporotic fractures from 2001 to 2024. A bibliometric analysis was performed using VOSviewer, CiteSpace, and R 4.3.3 for the publication volume, country and institution contributions, journal impact, author influence, and research hotspots. Results: A total of 214 articles were analyzed. Publication rates have steadily increased, with a peak of 21 papers in 2020. The U.S., China, and South Korea were the top contributing countries, and leading institutions included Harvard University and Dankook University. The Conclusion: This bibliometric analysis provides a comprehensive overview of RANKL research in osteoporotic fractures, highlighting key priorities for future investigation. Future studies should prioritize understanding RANKL's broader physiological roles, developing better predictive markers, and optimizing personalized treatment strategies.

Indexed as

bibliometric analysisbone metabolismosteoclast differentiationosteoporotic fracturesRANKL

Identifiers

PMID40206031
PMCPMC11978631

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.