ArticleVeterinary medicine and science2025
The Effect of Bovine Viral Diarrhoea Virus Biotypes on Bovine Oocyte In Vitro.
Article in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Delayed ovulation in cattle: Physiological mechanisms, diagnostic approaches, and reproductive management strategies.Veterinary world · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Bovine viral diarrhoea virus (BVDV) is a significant pathogen in the global cattle population, with two biotypes: cytopathic (CP) and non-cytopathic (NCP), differing in their effects on cell culture. This study aimed to examine the impact of BVDV on the expression of apoptosis-related genes and total antioxidant capacity (TAC) in vitro. Oocytes were obtained from post-slaughter bovine ovaries and infected with both BVDV biotypes in vitro. Gene expression levels of bcl 2, bax, caspase 3 and caspase 9 were assessed using reverse transcription-quantitative PCR (RT-qPCR). The results indicated significant differences in gene expression levels, with bcl 2 expression reduced in CP and NCP-infected oocytes compared to the control group (p < 0.05). Additionally, bax and caspase 3 expression levels were significantly elevated in the CP BVDV groups (p < 0.05). In the NCP BVDV groups, the expression of bcl 2 decreased (p < 0.05), while caspase 9 expression increased by 3.588-fold compared to the control group (p < 0.05). Furthermore, TAC levels in the CP groups were significantly lower than those in the control group (p < 0.05). These findings suggest that the CP biotype of BVDV markedly affects TAC and alters the expression of key apoptosis-related genes, while the NCP biotype reduces bcl 2 expression and increases caspase 9 expression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.