Evidence map›Paper›PMID 40205590›Full record

Observational studyBMC infectious diseases2025

Cardiac symptoms in patients 3-6 months after contracting COVID-19- data from the polish STOP-COVID registry.

Mateusz Babicki, Joanna Kapusta, Damian Kołat, Żaneta Kałuzińska-Kołat, Agnieszka Mastalerz-Migas, Piotr Jankowski, Michał Chudzik

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05018052 (Characteristics and Predictors of Early and Late Cardiovascular Complications of Covid-19 Patients - the PoLoCOV-Study), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05018052 unknown statusnot on this map

Characteristics and Predictors of Early and Late Cardiovascular Complications of Covid-19 Patients - the PoLoCOV-Study (Polish LONG-COVID Cardiovascular Study)

Typeobservational_patient_registrySponsorMichal ChudzikRan2020 to 2022Enrolled1,900ConditionsCovid19, LONG-COVID
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mateusz Babicki *Department of Family Medicine, Wroclaw Medical University, Wroclaw, 51-141, Poland.
Joanna Kapusta *Department of Internal Diseases, Rehabilitation and Physical Medicine, Medical University of Lodz, Lodz, 90-647, Poland. joanna.kapusta@umed.lodz.pl.
Damian KołatDepartment of Biomedicine and Experimental Surgery, Medical University of Lodz, Narutowicza 60, Lodz, 90-136, Poland.
Żaneta Kałuzińska-KołatDepartment of Biomedicine and Experimental Surgery, Medical University of Lodz, Narutowicza 60, Lodz, 90-136, Poland.
Agnieszka Mastalerz-MigasDepartment of Family Medicine, Wroclaw Medical University, Wroclaw, 51-141, Poland.
Piotr JankowskiDepartment of Internal Medicine and Geriatric Cardiology, Medical Centre for Postgraduate Education, Warsaw, 01-813, Poland.
Michał ChudzikDepartment of Internal Medicine and Geriatric Cardiology, Medical Centre for Postgraduate Education, Warsaw, 01-813, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCommon complaints of long COVID patients are cardiac symptoms such as fatigue, weakness, and a feeling of palpitations. The study aimed to investigate the clinical features of patients with persistent cardiological symptoms occurring within 3 to 6 months after COVID-19. Differences in ambulatory blood pressure monitoring (ABPM), Holter ECG (electrocardiogram) and Echocardiography between people with and without persistent cardiological symptoms were evaluated. We also assessed whether the symptoms of anxiety and depression may be implicated in the clinical outcomes. MATERIALS AND

methodsThis was a retrospective study of patients affiliated with the STOP-COVID registry who attended a follow-up visit 3-6 months after undergoing COVID-19. The visit assessed the clinical symptoms present and performed tests: ABPM, Holter ECG and Echocardiography. 504 patients additionally had GAD-2 (Generalized Anxiety Disorder 2-item) and PHQ-2 (Patient Health Questionnaire-2) tests performed.

resultsThe analysis included 1080 patients. At least 1 of the analyzed symptoms was present in 586 patients (54.3%). The most common symptom was fatigue (38.9%). Comparing patients with or without palpitations showed that the mean value of ventricular extrasystole was higher in the former group (p = 0.011). Comparing patients with and without cardiac symptoms, there were differences in the mean values of the PHQ-2 (p = 0.022) and GAD-2 (p < 0.001) scales, as well as in the percentage of responses related to the risk of anxiety or depression.

conclusionCardiological symptoms are common among health issues that patients must face after contracting COVID-19. People with palpitations had more excessive ventricular extrasystoles than patients without these symptoms.

trial registrationOur retrospective study was based on analysis of medical data of patients with COVID-19 treated on out-patient basis in the STOP-COVID registry of the Polish Long-Covid Cardiovascular (PoLoCOV-CVD) study (ClinicalTrials.gov identifier- NCT05018052, the registration date 29.05.2020). Consent to conduct the study was obtained from the Bioethics Committee of the District Medical Chamber in Lodz (no. KB-0115/2021).

Indexed as

COVID-19AdultAgedAnxietyBlood Pressure Monitoring, AmbulatoryDepressionEchocardiographyElectrocardiography, AmbulatoryFatigueFemaleHumansMaleMiddle AgedPolandRegistriesRetrospective StudiesCardiovascular diseaseCOVID-19Long COVIDOmicronSARS-CoV-2

Identifiers

PMID40205590
PMCPMC11983939

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.