Evidence map›Paper›PMID 40205550›Full record

ArticleBMC pediatrics2025

The impact of school periods and long holiday periods on the occurrence of neurally mediated syncope in children.

Shuo Wang, Ping Liu, Xiaohui Gong, Jizhi Xu, Tuoyu Gan, Yuwen Wang, Hong Cai, Runmei Zou, Cheng Wang

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Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Shuo WangDepartment of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
Ping LiuDepartment of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
Xiaohui GongDepartment of Pediatrics, Changsha Hospital for Maternal & Child Health Care Affiliated to Hunan Normal University, Changsha, 410007, China.
Jizhi XuDepartment of Pediatrics, Changsha Hospital for Maternal & Child Health Care Affiliated to Hunan Normal University, Changsha, 410007, China.
Tuoyu GanDepartment of Pediatrics, Changsha Hospital for Maternal & Child Health Care Affiliated to Hunan Normal University, Changsha, 410007, China.
Yuwen WangDepartment of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
Hong CaiDepartment of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
Runmei ZouDepartment of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
Cheng WangDepartment of Pediatrics, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China. wangcheng2nd@csu.edu.cn.ORCID http://orcid.org/0000-0002-7120-0654

Funding

Department of Science and Technology of Hunan Province 2023SK4018Natural Science Foundation of Hunan Province 2023JJ30812
6 · The paper itself

Abstract

objectiveTo explore the impact of school periods and long holiday periods on the occurrence of neurally mediated syncope (NMS) in children.

methodsA retrospective analysis was conducted on 262 children with NMS. The children were aged 4-17 years, 119 males. 244 cases were diagnosed as vasovagal syncope, and 18 cases as postural orthostatic tachycardia syndrome. The data on the age, sex, syncope triggers, hemodynamic types, family history of syncope of children with syncope during long holiday periods group (n = 68) and school periods group (n = 194) were compared.

results(1) Incidence of syncope: The incidence of syncope during school periods (74.05%) was higher than that during long holiday periods (25.95%). (2) Comparison of sex and triggers: The constituent ratio of females with syncope during school periods was higher than that of males (P < 0.05). Among the triggers, the proportion of sudden postural change during long holiday periods was higher than that during school periods (26.47% vs. 21.13%, P < 0.05). (3) Univariate analysis: Situational syncope was a potential protective factor when syncope occurred during school periods (OR 0.23, 95%CI 0.07-0.76, P < 0.05), and being female was a potential risk factor (OR 1.92, 95%CI 1.10-3.35, P < 0.05). (4) Comparison of multiple models: In the risk of syncope occurring during school periods, situational syncope reduced the risk by 79% compared with no trigger, and being female increased the risk by 78% compared with being male.

conclusionsThe occurrence of NMS-related syncope events in children is associated with school periods and long holiday periods. During school periods, being female is a risk factor for syncope, while situational syncope is a protective factor.

Indexed as

HolidaysPostural Orthostatic Tachycardia SyndromeSchoolsSyncope, VasovagalAdolescentChildChild, PreschoolFemaleHumansIncidenceMaleRetrospective StudiesRisk FactorsSex FactorsSyncopeTime FactorsChildrenHead-up Tilt testHemodynamic typeNeurally mediated syncopeSchool and holidays

Identifiers

PMID40205550
PMCPMC11983773

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.