ArticleJournal of health, population, and nutrition2025
Association between neutrophil to high-density lipoprotein cholesterol ratio and hearing loss: a cross-sectional study from NHANES.
Article in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Admission neutrophil-to-high-density lipoprotein cholesterol ratio and the risk of preoperative early rebleed in aneurysmal subarachnoid hemorrhage.European journal of medical research · 2025Article
- Neutrophil-to-High density lipoprotein cholesterol ratio predicts early hematoma expansion in patients with spontaneous intracerebral hemorrhage.Neurosurgical review · 2025Article
- Occupational Noise Exposure and High-Frequency Hearing Loss: A Comparative Study of Workers Across Multiple Industries.Noise & healthArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundThis study aimed to investigate the relationship between the neutrophil-to-HDL cholesterol ratio (NHR) and the risk of hearing loss, as well as to evaluate the potential of the NHR as a biomarker for hearing loss.
methodsThe U.S. National Health and Nutrition Examination Survey (NHANES) data covering 2005-2012 and 2015-2020 were analyzed. A weighted multivariate logistic regression model assessed the correlation between NHR and speech-frequency hearing loss (SFHL) and high-frequency hearing loss (HFHL). Restricted cubic spline (RCS) regression analysis was utilized to investigate the nonlinear correlation. Additionally, subgroup analysis was performed to identify differences among subgroups. A receiver operating characteristic (ROC) analysis was conducted to evaluate the efficacy of NHR in predicting hearing loss.
resultsA total of 10,436 participants were involved. After comprehensive adjustments for confounding factors, NHR was linearly correlated with SFHL and HFHL. Subgroup analysis revealed that race and the poverty index ratio (PIR) significantly modified the association between NHR and hearing loss. ROC analysis demonstrated the predictive capability of NHR for hearing loss.
conclusionNHR is positively correlated with the risk of hearing loss. This study suggests that NHR may serve as a potential biomarker for predicting and assessing hearing loss, demonstrating significant clinical application value. However, this cross-sectional study limits the ability to establish causality. Future longitudinal studies are needed to confirm these findings and explore potential mechanisms.
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Registered trials
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