Evidence map›Paper›PMID 40205482›Full record

ArticleJournal of medical case reports2025

An infant inflammatory myofibroblastoma with TFG-ROS1 fusion: a case report.

Hui Jiang, Junnan Jiang, Baidong Feng, Yaxian Yang, Qi Li, Bin Lian, Xiao Ding, Zhaodong Pan, Mingjian Huang, Zhaowen Pan and 1 more

Abstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hui JiangDepartment of Pathology, The Central Hospital of Yongzhou, Yongzhou, 425000, Hunan Province, China.
Junnan JiangDepartment of Pathology, The Central Hospital of Yongzhou, Yongzhou, 425000, Hunan Province, China.
Baidong FengDepartment of Neonatal, Maoming Maternal and Child Health Hospital, Maoming, 525000, Guangdong Province, China.
Yaxian YangGuangzhou Huayin Health Medical Group Co., Ltd, No. 33 Binhe Road, Huangpu District, Guangzhou, 510700, Guangdong Province, China.
Qi LiGuangzhou Huayin Health Medical Group Co., Ltd, No. 33 Binhe Road, Huangpu District, Guangzhou, 510700, Guangdong Province, China.
Bin LianGuangzhou Huayin Health Medical Group Co., Ltd, No. 33 Binhe Road, Huangpu District, Guangzhou, 510700, Guangdong Province, China.
Xiao DingGuangzhou Huayin Health Medical Group Co., Ltd, No. 33 Binhe Road, Huangpu District, Guangzhou, 510700, Guangdong Province, China.
Zhaodong PanGuangzhou Huayin Health Medical Group Co., Ltd, No. 33 Binhe Road, Huangpu District, Guangzhou, 510700, Guangdong Province, China.
Mingjian HuangGuangzhou Huayin Health Medical Group Co., Ltd, No. 33 Binhe Road, Huangpu District, Guangzhou, 510700, Guangdong Province, China.
Zhaowen PanGuangzhou Huayin Health Medical Group Co., Ltd, No. 33 Binhe Road, Huangpu District, Guangzhou, 510700, Guangdong Province, China.
Jian HuangGuangzhou Huayin Health Medical Group Co., Ltd, No. 33 Binhe Road, Huangpu District, Guangzhou, 510700, Guangdong Province, China. huangjian_hy@126.com.

Funding

National Natural Science Foundation of China 81572610
6 · The paper itself

Abstract

backgroundInflammatory myofibroblastic tumors are extremely rare in the neck of infants, and pathological diagnosis may be challenging. Kinase fusions play an important role in the biology of many inflammatory myofibroblastic tumors, becoming an effective diagnostic method. CASE PRESENTATION: In this report, we present the case of an East Asian (Han Chinese) patient with rare infant inflammatory myofibroblastoma. DNA-based but not RNA-based next-generation sequencing was used to identify its targetable ROS1 fusions.

conclusionThis case highlights the importance of simultaneously detecting DNA and RNA using next-generation sequencing in clinical practice.

Indexed as

Neoplasms, Muscle TissueProtein-Tyrosine KinasesProto-Oncogene ProteinsFemaleHigh-Throughput Nucleotide SequencingHumansInfantMaleProtein-Tyrosine KinasesProto-Oncogene ProteinsROS1 protein, humanGene fusionInflammatory myofibroblastomaMolecular pathologyROS1

Identifiers

PMID40205482
PMCPMC11984052

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.