ArticleDiabetology & metabolic syndrome2025
Effect of atherogenic index of plasma and triglyceride-glucose index on early neurological deterioration of patients with large artery atherosclerotic ischemic stroke.
Article in Diabetology & metabolic syndrome, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Atherogenic index of plasma in stroke: A comprehensive review of its diagnostic, prognostic, and pathophysiological significance.World journal of clinical cases · 2026Review
- Cumulative inflammatory, coagulation, and metabolic abnormalities predict poor 90-day functional outcome after endovascular thrombectomy for large-vessel occlusion acute ischemic stroke.Frontiers in neurology · 2026Article
- Identification of key metabolic indicators associated with the comorbidity of ischemic stroke and diabetes mellitus using an optimal interpretable clinlabomics model.Frontiers in cardiovascular medicine · 2026Article
- Association between atherogenic index of plasma and sepsis in critically ill patients with ischemic stroke: a retrospective cohort study using propensity score and machine learning approaches.Lipids in health and disease · 2025Article
- Atherogenic Index of Plasma Predicts Futile Reperfusion and Early Deterioration After Successful Recanalization: A Multicenter Study of EVT-Treated LAA Stroke.Biomedicines · 2025Article
- TyG-BMI as a predictor of ischemic stroke over 10 years in middle-aged and older adults: findings from the China cardiometabolic disease and cancer cohort (4C) study.Frontiers in neurology · 2025Article
- Association of atherogenic index of plasma with early-onset post-stroke depression: a prospective study.Frontiers in psychiatry · 2025Article
- Association between the atherogenic index of plasma and the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio with early neurological deterioration after thrombolysis.Frontiers in neurology · 2025Article
- Cardiometabolic index and modified cardiometabolic index are associated with early neurological deterioration in patients with acute ischemic stroke.Frontiers in neurologyArticle
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3 authors.
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Abstract
backgroundStroke due to large artery atherosclerosis (LAA-stroke) has a poor early prognosis despite appropriate medical treatment. Recently, various parameters reflecting pathological conditions such as insulin resistance or atherogenic dyslipidemia have been proposed using triglyceride (TG) and other biomarkers. In this study, we evaluated the association between TG andTG-related parameters and early neurological deterioration (END) in patients with acute LAA stroke.
methodsWe evaluated consecutive patients with acute LAA-stroke between January 2010 and December 2020. TG-related parameters were calculated using the following formulas: the atherogenic index of plasma (AIP) = log
resultsSix hundred and forty patients with acute LAA-stroke were evaluated. In multivariable analyses, AIP (adjusted odds ratio [aOR]: 1.93, 95% confidence interval: 1.32-2.82) was closely associated with END after adjustment for confounders. The TyG index (aOR: 2.22, 95% confidence interval: 1.51-3.27) also showed close association with END. The AIP and TyG index showed significant differences between the END and no END groups only in patients with LAA-stroke caused by intracranial atherosclerosis. In addition, AIP and TyG index were closely related to END only in patients with LAA-stroke caused by artery-to-artery embolism and branch atheromatous disease mechanisms.
conclusionsWe found that TG and TG-related parameters were associated with the occurrence of END in patients with acute LAA-stroke. This association appeared differently depending on the location or mechanism of the relevant vessel that caused LAA-stroke.
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