ArticleBMC gastroenterology2025
The fasting plasma glucose to high-density lipoprotein cholesterol ratio: a novel index for identifying NAFLD.
Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Association of AGAHR with metabolic dysfunction-associated steatotic liver disease (MASLD).Hormones (Athens, Greece) · 2026Article
- Association Between Thyroid Hormone Sensitivity and Non-Alcoholic Fatty Liver Disease in Individuals with Normal Thyroid Function.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Relationship Between Fasting Blood Glucose to High-Density Lipoprotein Cholesterol Ratio (GHR) and Coronary Artery Vascular Lesions: A Retrospective Cross-Sectional Study.International journal of general medicine · 2025Article
- Independent and joint associations of glucose modified by high-density lipoprotein cholesterol with mortality in heart failure patients: evidence from the Jiangxi, China cohort.Frontiers in endocrinology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
backgroundPrevious research has indicated that the fasting plasma glucose to high-density lipoprotein cholesterol ratio (FHR) is a novel biomarker for assessing cardiovascular disease prognosis. The objective of this study is to investigate the potential relationship of FHR with non-alcoholic fatty liver disease (NAFLD).
methodsThe present study employed a retrospective design and included 14,251 participants who underwent health examinations. Restricted cubic spline regression and multivariable logistic regression were used to assess the relationship of NAFLD with FHR. The performance of the FHR in identifying NAFLD was analyzed through receiver operating curve analysis.
resultsAfter adjustment for confounders, a positive association of FHR with NAFLD was observed in the multivariable logistic regression model. Compared to the lowest FHR quartile, the odds ratios for the 2, 3, and 4 quartiles were 1.49 (1.14, 1.94), 2.03 (1.57, 2.63), and 2.34 (1.79, 3.06), respectively. Additionally, restricted cubic spline regression analysis revealed a nonlinear relationship of FHR with NAFLD prevalence with a potential threshold effect. The prevalence of NAFLD remained nearly unchanged when the FHR was less than 3, but increased progressively when the ratio exceeded 3. Further receiver operating curve analysis demonstrated that the FHR significantly outperformed fasting plasma glucose or high-density lipoprotein cholesterol alone in identifying NAFLD, with an optimal threshold identified at 3.89.
conclusionThe FHR is a new index used to identify NAFLD, and the incorporation of the FHR into the risk stratification assessment system for NAFLD may be of significant help.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.