Evidence map›Paper›PMID 40205275›Full record

ArticleMolecular imaging and biology2025

Synthesis and Construction of I-124 Labeled Small Molecular Probe for Noninvasive PET Imaging of CAIX Expression.

Xianteng Yang, Chengxue He, Feng Wang, Li Wen, Haifeng Huang, Jing Wang, Zhi Yang, Hua Zhu

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular imaging and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Molecular imaging and biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xianteng Yang *Department of Orthopedics, Guizhou Provincial People's Hospital, Guiyang, 550002, China.
Chengxue He *Department of Nuclear Medicine, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Beijing Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital & Institute, Beijing, 100142, China.
Feng Wang *Department of Nuclear Medicine, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Beijing Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital & Institute, Beijing, 100142, China.
Li WenDepartment of Nuclear Medicine, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Beijing Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital & Institute, Beijing, 100142, China.
Haifeng HuangDepartment of Orthopedics, Guizhou Provincial People's Hospital, Guiyang, 550002, China.
Jing WangDepartment of Chemical Biology, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Zhi YangDepartment of Nuclear Medicine, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Beijing Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital & Institute, Beijing, 100142, China. pekyz@163.com.
Hua ZhuDepartment of Nuclear Medicine, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Beijing Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital & Institute, Beijing, 100142, China. zhuhuananjing@163.com.

Funding

Guizhou Provincial Science and Technology Department ZK[2024]481National Natural Science Foundation of China 81960538
6 · The paper itself

Abstract

purposeCarbonic anhydrase IX (CAIX) which is high expression in the most of hypoxic tumor than normal tissue, promoting the growth, invasion, and metastasis of the tumor. Therefore, the study aimed to evaluate the retention and diagnostic ability of [ PROCEDURES: [

results[

conclusionThe study have shown that [

Indexed as

Antigens, NeoplasmCarbonic Anhydrase IXIodine RadioisotopesMolecular ProbesPositron-Emission TomographyAnimalsCell Line, TumorHT29 CellsHumansMiceMice, Inbred BALB CMice, NudeTissue DistributionAntigens, NeoplasmCA9 protein, humanCarbonic Anhydrase IXIodine-124Iodine RadioisotopesMolecular Probes[124/125I]I-XYIMSR- 01Carbonic anhydrase IXHuman colon cancerPositron emission tomography imaging

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.