Evidence map›Paper›PMID 40205272›Full record

ReviewTopics in current chemistry (Cham)2025

Polymer Anchored Cinchona Alkaloids: Synthesis and their Applications in Organo-Catalysis.

Patra Haripriya, Rajat Rai, Kari Vijayakrishna

Abstract readReview
PubMed Publisher
In one paragraph

Review in Topics in current chemistry (Cham), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Patra Haripriya *Department of Chemistry, School of Basic Sciences, Indian Institute of Technology, Bhubaneswar, Odisha, 752050, India.
Rajat Rai *Department of Chemistry, School of Basic Sciences, Indian Institute of Technology, Bhubaneswar, Odisha, 752050, India.
Kari VijayakrishnaDepartment of Chemistry, School of Basic Sciences, Indian Institute of Technology, Bhubaneswar, Odisha, 752050, India. kvijayakrishna@iitbbs.ac.in.

Funding

Science and Engineering Research Board CRG/2020/003754
6 · The paper itself

Abstract

Cinchona alkaloids are naturally occurring chiral molecules that have emerged as catalysts in asymmetric organocatalysis especially in enantioselective transformations because of their inherent chirality and unique structural features. Immobilizing these alkaloids on polymeric supports has significantly influenced their use in catalysis. Polymer-anchored cinchona alkaloids combine the catalytic efficacy of cinchona derivatives with additional benefits of polymer chain, such as ease of recovery, recyclability, reusability, and reduced environmental impact. These polymer-supported cinchona alkaloids have found wide applications in enantioselective reactions such as Michael addition, aldol condensations, Henry reaction, dimerization reaction, dihydroxylation, and benzylation. Various strategies have been employed for anchoring cinchona alkaloids onto polymers, including covalent attachment of alkaloids in the polymer side chain or main chain, and ionic attachment of alkaloids via quaternization in the main chain or side chain of polymer. This review focuses on the various synthetic methodologies for the preparation of polymer-anchored cinchona alkaloids and their application in numerous asymmetric transformations.

Indexed as

Cinchona AlkaloidsPolymersCatalysisMolecular StructureStereoisomerismCinchona AlkaloidsPolymersAsymmetic synthesisCinchona alkaloidsOrganocatalysisPolymer supportedRecyclable catalyst

Identifiers

PMID40205272

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.