Evidence map›Paper›PMID 40205235›Full record

ArticleMolecular biology reports2025

Transcriptomic insights into the effects of monocrotophos on Chrysomya megacephala: forensic implications of altered pupation time.

V V Renu, Y Shibu Vardhanan

Abstract read
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In one paragraph

Article in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

V V RenuBiochemistry & Toxicology Division, Department of Zoology, University of Calicut, Kerala, 673635, India. renuvenugopal.vtm@gmail.com.ORCID https://orcid.org/0000-0001-7988-8812
Y Shibu VardhananBiochemistry & Toxicology Division, Department of Zoology, University of Calicut, Kerala, 673635, India.ORCID https://orcid.org/0000-0001-9820-886X

Funding

Human Resource Development Centre, Council of Scientific And Industrial Research 09/043(0202)/2019-EMR-1
6 · The paper itself

Abstract

backgroundChrysomya megacephala is a forensically important dipteran that significantly facilitates the estimation of Post Mortem Interval (PMI) in forensic entomology. In this study, we investigated the sublethal effects of monocrotophos, a widely used insecticide, on third-instar larvae of Chrysomya megacephala. METHODS AND

resultsThe EC

conclusionsMolecular expression profiling showed 17,865 Differentially Expressed Genes, among which 8,731 were downregulated, and 9,134 were upregulated. Functional annotation (KOG) and pathway enrichment analysis (GO and KEGG) revealed that the effect of monocrotophos alters the expression of a significant number of genes involved in various biological processes, including amino acid, carbohydrate, and lipid transportation and metabolism; proteolysis; monooxygenase activity; regulatory RNA binding; regulation of gene expression; signal transduction; xenobiotics biodegradation and metabolism; and glycan biosynthesis and metabolism.

Indexed as

CalliphoridaeMonocrotophosTranscriptomeAnimalsForensic EntomologyGene Expression ProfilingInsecticidesLarvaPupaInsecticidesMonocrotophosCalliphoridaeChrysomya megacephalaDifferential gene expressionEntomotoxicologyPupationTranscriptome profiling

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.