Evidence map›Paper›PMID 40205216›Full record

ArticleNature2025

Perisomatic ultrastructure efficiently classifies cells in mouse cortex.

Leila Elabbady, Sharmishtaa Seshamani, Shang Mu, Gayathri Mahalingam, Casey M Schneider-Mizell, Agnes L Bodor, J Alexander Bae, Derrick Brittain, JoAnn Buchanan, Daniel J Bumbarger and 28 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Leila ElabbadyAllen Institute for Brain Science, Seattle, WA, USA.
Sharmishtaa SeshamaniAllen Institute for Brain Science, Seattle, WA, USA.
Shang MuPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Gayathri MahalingamAllen Institute for Brain Science, Seattle, WA, USA.
Casey M Schneider-MizellAllen Institute for Brain Science, Seattle, WA, USA.ORCID 0000-0001-9477-3853
Agnes L BodorAllen Institute for Brain Science, Seattle, WA, USA.
J Alexander BaePrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-4681-6342
Derrick BrittainAllen Institute for Brain Science, Seattle, WA, USA.
JoAnn BuchananAllen Institute for Brain Science, Seattle, WA, USA.ORCID 0000-0002-4212-5560
Daniel J BumbargerAllen Institute for Brain Science, Seattle, WA, USA.
Manuel A CastroPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Sven DorkenwaldAllen Institute for Brain Science, Seattle, WA, USA.
Akhilesh HalageriPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Zhen JiaPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Chris JordanPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Dan KapnerAllen Institute for Brain Science, Seattle, WA, USA.
Nico KemnitzPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-0260-4532
Sam KinnAllen Institute for Brain Science, Seattle, WA, USA.
Kisuk LeePrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Kai LiPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-2095-7024
Ran LuPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Thomas MacrinaPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Eric MitchellPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-7487-1744
Shanka Subhra MondalPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0000-0003-1252-0129
Barak NehoranPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0000-0001-7371-0829
Sergiy PopovychPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
William SilversmithPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Marc TakenoAllen Institute for Brain Science, Seattle, WA, USA.ORCID 0000-0002-8384-7500
Russel TorresAllen Institute for Brain Science, Seattle, WA, USA.ORCID 0000-0002-2876-4382
Nicholas L TurnerPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
William WongPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Jingpeng WuPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Wenjing YinAllen Institute for Brain Science, Seattle, WA, USA.
Szi-Chieh YuPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0009-0001-9684-0156
H Sebastian SeungPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-8591-6733
R Clay ReidAllen Institute for Brain Science, Seattle, WA, USA.ORCID 0000-0002-8697-6797
Nuno Maçarico da CostaAllen Institute for Brain Science, Seattle, WA, USA.ORCID 0000-0003-2001-4568
Forrest CollmanAllen Institute for Brain Science, Seattle, WA, USA. forrestc@alleninstitute.org.ORCID 0000-0002-0280-7022

Funding

Structure and Function of a Cubic Millimeter of Cortex: Crowdsourcing for Proofreading and DiscoveryRF1MH123400 · NIMH · PRINCETON UNIVERSITY · PI SEUNG, HYUNJUNE SEBASTIAN · 2020 to 2020
$6.4M
Dissemination of FlyWire, A Whole-Brain Connectomics ResourceU24NS126935 · NINDS · PRINCETON UNIVERSITY · PI Mala Murthy · 2022 to 2026
$5.6M
Tools to broaden access to high-throughput functional connectomicsRF1MH117808 · NIMH · HARVARD MEDICAL SCHOOL · PI LEE, WEI-CHUNG ALLEN, MACRINA, THOMAS · 2019 to 2019
$4.3M
Accelerating connectomic proofreading for larger brains and multiple individualsRF1MH129268 · NIMH · PRINCETON UNIVERSITY · PI MURTHY, MALA · 2022 to 2022
$2.1M
From synapses to genes through morphology: an integrated characterization of cell types based on connectomics and transcriptomics dataRF1MH125932 · NIMH · ALLEN INSTITUTE · PI COLLMAN, FORREST CHRISTIE, MACARICO DA COSTA, NUNO · 2021 to 2021
$1.4M
NIMH NIH HHS RF1 MH117808NIMH NIH HHS RF1 MH123400NIMH NIH HHS RF1 MH125932NIMH NIH HHS RF1 MH129268NINDS NIH HHS U24 NS126935
6 · The paper itself

Abstract

Mammalian neocortex contains a highly diverse set of cell types. These cell types have been mapped systematically using a variety of molecular, electrophysiological and morphological approaches

Indexed as

Classification AlgorithmsNeocortexNeuronsAnimalsAutoencoderCell NucleusDatasets as TopicDNA PrimaseMaleMiceMice, KnockoutMicroscopy, ElectronSynapsesDNA Primase

Identifiers

PMID40205216
PMCPMC11981918

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.